CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036598
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transforming acidic coiled-coil-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 TACC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
141ISAVLGTKAAHGCVTubiquitination[1]
258LGDARFQKSPPDLKEubiquitination[1]
332IQKDGISKSAGLEQPubiquitination[1, 2]
489ASTSCGQKSAGAEVKubiquitination[2]
496KSAGAEVKGIEKETCubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 557 AA 
Protein Sequence
MGGSHSQTPR GREPAGERHP RPTETASDSE GNFETPEAET PIRSPFKESC DPSLGLAGPG 60
AKSQESQEAD EQLVAEVVEK CSSKTCSKPS ENEVPQQAID SHSVKNFREE PEHDFSKISI 120
VRPFSIETKD STDISAVLGT KAAHGCVTAV SGKALPSSPP DALQDEAMTE GSMGVTLEAS 180
AEADLKAGNS CPELVPSRRS KLRKPKPVPL RKKAIGGEFS DTNAAVEGTP LPKASYHFSP 240
EELDENTSPL LGDARFQKSP PDLKETPGTL SSDTNDSGVE LGEESRSSPL KLEFDFTEDT 300
GNIEARKALP RKLGRKLGST LTPKIQKDGI SKSAGLEQPT DPVARDGPLS QTSSKPDPSQ 360
WESPSFNPFG SHSVLQNSPP LSSEGSYHFD PDNFDESMDP FKPTTTLTSS DFCSPTGNHV 420
NEILESPKKA KSRLITSGCK VKKHETQSLA LDACSRDEGA VISQISDISN RDGHATDEEK 480
LASTSCGQKS AGAEVKGIEK ETCQKMEEDG STVLGLLESS AEKAPVSVSC GGESPLDGIC 540
LSESDKTAVL TLIREEV 557 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0015630; C:microtubule cytoskeleton; IDA:HPA. 
Interpro
 IPR007707; TACC. 
Pfam
  
SMART
  
PROSITE
  
PRINTS