CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040112
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acetyl-CoA carboxylase 2 
Protein Synonyms/Alias
  
Gene Name
 ACACB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
79LYSEDDCKSLREEPIubiquitination[1]
139AQEKEFPKFFTFRARubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 858 AA 
Protein Sequence
MTVPISITNP DLLRHSTELF MDSGFSPLCQ RMGAMVAFRR FEDFTRNFDE VISCFANVPK 60
DTPLFSEART SLYSEDDCKS LREEPIHILN VSIQCADHLE DEALVPILRT FVQSKKNILV 120
DYGLRRITFL IAQEKEFPKF FTFRARDEFA EDRIYRHLEP ALAFQLELNR MRNFDLTAVP 180
CANHKMHLYL GAAKVKEGVE VTDHRFFIRA IIRHSDLITK EASFEYLQNE GERLLLEAMD 240
ELEVAFNNTS VRTDCNHIFL NFVPTVIMDP FKIEESVRYM VMRYGSRLWK LRVLQAEVKI 300
NIRQTTTGSA VPIRLFITNE SGYYLDISLY KEVTDSRSGN IMFHSFGNKQ GPQHGMLINT 360
PYVTKDLLQA KRFQAQTLGT TYIYDFPEMF RQALFKLWGS PDKYPKDILT YTELVLDSQG 420
QLVEMNRLPG GNEVGMVAFK MRFKTQEYPE GRDVIVIGND ITFRIGSFGP GEDLLYLRAS 480
EMARAEGIPK IYVAANSGAR IGMAEEIKHM FHVAWVDPED PHKGFKYLYL TPQDYTRISS 540
LNSVHCKHIE EGGESRYMIT DIIGKDDGLG VENLRGSGMI AGESSLAYEE IVTISLVTCR 600
AIGIGAYLVR LGQRVIQVEN SHIILTGASA LNKVLGREVY TSNNQLGGVQ IMHYNGVSHI 660
TVPDDFEGVY TILEWLSYMP KDNHSPVPII TPTDPIDREI EFLPSRAPYD PRWMLAGRPH 720
PTLKGTWQSG FFDHGSFKEI MAPWAQTVVT GRARLGGIPV GVIAVETRTV EVAVPADPAN 780
LDSEAKIIQQ AGQVWFPDSA YKTAQAVKDF NREKLPLMIF ANWRGFSGGM KGCLGTWRDV 840
SWWKIRAMLP MHIGEGSV 858 
Gene Ontology
 GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro. 
Interpro
 IPR013537; AcCoA_COase_cen.
 IPR000022; Carboxyl_trans.
 IPR011763; COA_CT_C.
 IPR011762; COA_CT_N. 
Pfam
 PF08326; ACC_central
 PF01039; Carboxyl_trans 
SMART
  
PROSITE
 PS50989; COA_CT_CTER
 PS50980; COA_CT_NTER 
PRINTS