CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003209
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lipopolysaccharide export system ATP-binding protein LptB 
Protein Synonyms/Alias
  
Gene Name
 lptB 
Gene Synonyms/Alias
 yhbG; b3201; JW3168 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
177PISVIDIKRIIEHLRacetylation[1]
231ILQDEHVKRVYLGEDacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. 
Sequence Annotation
 DOMAIN 4 237 ABC transporter.
 NP_BIND 36 43 ATP (Potential).  
Keyword
 ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 241 AA 
Protein Sequence
MATLTAKNLA KAYKGRRVVE DVSLTVNSGE IVGLLGPNGA GKTTTFYMVV GIVPRDAGNI 60
IIDDDDISLL PLHARARRGI GYLPQEASIF RRLSVYDNLM AVLQIRDDLS AEQREDRANE 120
LMEEFHIEHL RDSMGQSLSG GERRRVEIAR ALAANPKFIL LDEPFAGVDP ISVIDIKRII 180
EHLRDSGLGV LITDHNVRET LAVCERAYIV SQGHLIAHGT PTEILQDEHV KRVYLGEDFR 240
L 241 
Gene Ontology
 GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IDA:EcoCyc.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0015437; F:lipopolysaccharide-transporting ATPase activity; IDA:EcoCyc.
 GO:0015920; P:lipopolysaccharide transport; IMP:EcoCyc. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS