| Tag | Content |
|---|
| CPLM ID | CPLM-018124 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glycogen [starch] synthase, liver |
Protein Synonyms/Alias | |
Gene Name | Gys2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 53 | TVIQTKAKTTADEWG | ubiquitination | [1] | | 97 | KAVDAMNKHGCQVHF | ubiquitination | [1] | | 273 | AEHMLKRKPDVVTPN | ubiquitination | [1] | | 381 | NFNVETLKGQAVRKQ | ubiquitination | [1] | | 387 | LKGQAVRKQLWDTVH | ubiquitination | [1] | | 397 | WDTVHCLKEKFGKKL | ubiquitination | [1] | | 403 | LKEKFGKKLYDGLLR | ubiquitination | [1] | | 429 | RDDLTIMKRAIFSTQ | ubiquitination | [1] | | 620 | LSRAFPDKFHLEPTS | ubiquitination | [1] | | 683 | ERDRLNIKSPFSLNH | ubiquitination | [1] | | 693 | FSLNHFPKGKKKLHG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. |
Sequence Annotation | BINDING 40 40 UDP-glucose (By similarity).
MOD_RES 6 6 Phosphoserine.
MOD_RES 8 8 Phosphoserine.
MOD_RES 11 11 Phosphoserine.
MOD_RES 626 626 Phosphothreonine.
MOD_RES 641 641 Phosphoserine; by GSK3-alpha and GSK3-
MOD_RES 645 645 Phosphoserine; by GSK3-alpha and GSK3-
MOD_RES 649 649 Phosphoserine; by GSK3-alpha and GSK3-
MOD_RES 653 653 Phosphoserine; by GSK3-alpha and GSK3-
MOD_RES 657 657 Phosphoserine; by CK2 (By similarity). |
Keyword | Allosteric enzyme; Complete proteome; Glycogen biosynthesis; Glycosyltransferase; Phosphoprotein; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 704 AA |
Protein Sequence | MLRGRSLSVT SLGGLPVWEA ERLPVEDLLL FEVSWEVTNK VGGICTVIQT KAKTTADEWG 60
ENYFLIGPYF EHNMKTQVEQ CEPTNDAVRK AVDAMNKHGC QVHFGRWLIE GSPYVVLFDI 120
SSSAWNLDRW KGDFWEACGV GIPHHDREAN DMLIFGSLTA WFLKEVTDHA DGKHVIAQFH 180
EWQAGTGLIL SRARKLPIAT VFTTHATLLG RYLCAANIDF YNQLDKFDID KEAGERQIYH 240
RYCMERASVH CAHVFTTVSE ITAIEAEHML KRKPDVVTPN GLNVKKFSAV HEFQNLHAMY 300
KARIQDFVRG HFYGHLDFDL EKTLFLFIAG RYEFSNKGAD IFLESLSRLN FLLRMHKSNV 360
TVVVFFIMPA KTNNFNVETL KGQAVRKQLW DTVHCLKEKF GKKLYDGLLR GEIPDMNSIL 420
DRDDLTIMKR AIFSTQRQSL PPVTTHNMID DSTDPILSTI RRIGLFNNRA DRVKVILHPE 480
FLSSTSPLLP MDYEEFVRGC HLGVFPSYYE PWGYTPAECT VMGIPSVTTN LSGFGCFVQE 540
HVADPTAYGI YIVDRRFRSP DDSCNQLTQF LYGFCKQSRR QRIIQRNRTE RLSDLLDWRY 600
LGRYYQHARH LTLSRAFPDK FHLEPTSPPT TDGFKYPRPS SVPPSPSGSQ ASSPQCSDAE 660
DEEDEDERYD EEEEAERDRL NIKSPFSLNH FPKGKKKLHG EYKN 704 |
Gene Ontology | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. GO:0005829; C:cytosol; ISS:UniProtKB. GO:0043265; C:ectoplasm; ISS:UniProtKB. GO:0004373; F:glycogen (starch) synthase activity; ISS:UniProtKB. GO:0005978; P:glycogen biosynthetic process; ISS:UniProtKB. GO:0009749; P:response to glucose stimulus; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |