CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Interleukin-9 receptor 
Protein Synonyms/Alias
 IL-9 receptor; IL-9R; CD129 
Gene Name
 IL9R 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
94QAPGGTHKCILRGSEubiquitination[1]
187SYELAFKKQEEAWEQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 This is a receptor for interleukin-9. 
Sequence Annotation
 DOMAIN 150 244 Fibronectin type-III.
 MOTIF 245 249 WSXWS motif.
 MOTIF 301 309 Box 1 motif.
 CARBOHYD 117 117 N-linked (GlcNAc...) (Potential).
 CARBOHYD 156 156 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Membrane; Polymorphism; Receptor; Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 521 AA 
Protein Sequence
MGLGRCIWEG WTLESEALRR DMGTWLLACI CICTCVCLGV SVTGEGQGPR SRTFTCLTNN 60
ILRIDCHWSA PELGQGSSPW LLFTSNQAPG GTHKCILRGS ECTVVLPPEA VLVPSDNFTI 120
TFHHCMSGRE QVSLVDPEYL PRRHVKLDPP SDLQSNISSG HCILTWSISP ALEPMTTLLS 180
YELAFKKQEE AWEQAQHRDH IVGVTWLILE AFELDPGFIH EARLRVQMAT LEDDVVEEER 240
YTGQWSEWSQ PVCFQAPQRQ GPLIPPWGWP GNTLVAVSIF LLLTGPTYLL FKLSPRVKRI 300
FYQNVPSPAM FFQPLYSVHN GNFQTWMGAH GAGVLLSQDC AGTPQGALEP CVQEATALLT 360
CGPARPWKSV ALEEEQEGPG TRLPGNLSSE DVLPAGCTEW RVQTLAYLPQ EDWAPTSLTR 420
PAPPDSEGSR SSSSSSSSNN NNYCALGCYG GWHLSALPGN TQSSGPIPAL ACGLSCDHQG 480
LETQQGVAWV LAGHCQRPGL HEDLQGMLLP SVLSKARSWT F 521 
Gene Ontology
 GO:0005615; C:extracellular space; TAS:ProtInc.
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0004919; F:interleukin-9 receptor activity; TAS:ProtInc.
 GO:0008283; P:cell proliferation; TAS:ProtInc. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR003531; Hempt_rcpt_S_F1_CS.
 IPR013783; Ig-like_fold. 
Pfam
  
SMART
  
PROSITE
 PS50853; FN3
 PS01355; HEMATOPO_REC_S_F1 
PRINTS