CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 79 
Protein Synonyms/Alias
 ZNFpT7 
Gene Name
 ZNF79 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
303QRIHTGEKPYECSDCubiquitination[1]
312YECSDCGKAFRHSANubiquitination[1]
359QRIHTGEKPYRCAACubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 38 109 KRAB.
 ZN_FING 193 215 C2H2-type 1.
 ZN_FING 221 243 C2H2-type 2.
 ZN_FING 249 271 C2H2-type 3.
 ZN_FING 277 299 C2H2-type 4.
 ZN_FING 305 327 C2H2-type 5.
 ZN_FING 333 355 C2H2-type 6.
 ZN_FING 361 383 C2H2-type 7.
 ZN_FING 389 411 C2H2-type 8.
 ZN_FING 417 439 C2H2-type 9.
 ZN_FING 445 467 C2H2-type 10.
 ZN_FING 473 495 C2H2-type 11.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 498 AA 
Protein Sequence
MLEEGVLPSP GPALPQEENT GEEGMAAGLL TAGPRGSTFF SSVTVAFAQE RWRCLVSTPR 60
DRFKEGIPGK SRSLVLLGLP VSQPGMNSQL EQREGAWMLE GEDLRSPSPG WKIISGSPPE 120
QALSEASFQD PCVEMPPGDS DHGTSDLEKS FNLRPVLSPQ QRVPVEARPR KCETHTESFK 180
NSEILKPHRA KPYACNECGK AFSYCSSLSQ HQKSHTGEKP YECSECGKAF SQSSSLIQHQ 240
RIHTGEKPYK CSECGRAFSQ NANLTKHQRT HTGEKPYRCS ECEKAFSDCS ALVQHQRIHT 300
GEKPYECSDC GKAFRHSANL TNHQRTHTGE KPYKCSECGK AFSYCAAFIQ HQRIHTGEKP 360
YRCAACGKAF SQSANLTNHQ RTHTGEKPYK CSECGKAFSQ STNLIIHQKT HTGEKPYKCN 420
ECGKFFSESS ALIRHHIIHT GEKPYECNEC GKAFNQSSSL SQHQRIHTGV KPYECSECGK 480
AFRCSSAFVR HQRLHAGE 498 
Gene Ontology
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS