CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025933
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin-like modifier-activating enzyme 1 
Protein Synonyms/Alias
  
Gene Name
 UBA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
199FCHNRGIKLVVADTRubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MLCVIYHLDN PVGKMSSSPL SKKRRVSGPD PKPGSNCSPA QSVLSEVPSV PTNGMAKNGS 60
EADIDEGLYS RQLYVLGHEA MKRLQTSSVL VSGLRGLGVE IAKNIILGGV KAVTLHDQGT 120
AQWADLSSQF YLREEDIGKN RAEVSQPRLA ELNSYVPVTA YTGPLVEDFL SGFQVVVLTN 180
TPLEDQLRVG EFCHNRGIKL VVADTRGLFG QLFCDFGEEM ILTDSNGEQP LSAMVSMVTK 240
DNPGVVTCLD EARHGFESGD FVSFSEVQGM VELNGNQPME IKVL 284 
Gene Ontology
 GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
 GO:0006464; P:cellular protein modification process; IEA:InterPro. 
Interpro
 IPR009036; Molybdenum_cofac_synth_MoeB.
 IPR016040; NAD(P)-bd_dom.
 IPR000594; ThiF_NAD_FAD-bd.
 IPR000011; UBQ/SUMO-activ_enz_E1-like. 
Pfam
 PF00899; ThiF 
SMART
  
PROSITE
  
PRINTS
 PR01849; UBIQUITINACT.