UniProt Accession

 TAL1_YEAST; P15019; D6VYZ2 

Genbank Protein ID

 X15953; U19102; X04969; L37016; BK006945 

Genbank Nucleotide ID

 CAA34078.1; AAB67752.1; CAA28644.1; AAA64519.1; DAA09658.1 

Protein Name

 Transaldolase 

Protein Synonyms/Alias

  

Gene Name

 TAL1 

Gene Synonyms/Alias

 YLR354C; L9638.6 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
56	SLILAAAKQPTYAKL	acetylation	[1]
56	SLILAAAKQPTYAKL	ubiquitination	[2]
76	EYGKKHGKTTEEQVE	ubiquitination	[2]
95	RLLVEFGKEILKIVP	ubiquitination	[2]
99	EFGKEILKIVPGRVS	acetylation	[1]
123	DTQATIEKARHIIKL	ubiquitination	[2]
129	EKARHIIKLFEQEGV	acetylation	[1]
138	FEQEGVSKERVLIKI	acetylation	[1]
138	FEQEGVSKERVLIKI	ubiquitination	[2]
144	SKERVLIKIASTWEG	ubiquitination	[2]
156	WEGIQAAKELEEKDG	ubiquitination	[2]
200	GRILDWYKSSTGKDY	acetylation	[1]
208	SSTGKDYKGEADPGV	acetylation	[1]
231	YYKKYGYKTIVMGAS	acetylation	[1]
246	FRSTDEIKNLAGVDY	ubiquitination	[2]
287	AKKEAGDKISYISDE	acetylation	[1]
296	SYISDESKFRFDLNE	acetylation	[1]
296	SYISDESKFRFDLNE	ubiquitination	[2]
310	EDAMATEKLSEGIRK	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. 

Sequence Annotation

 ACT_SITE 144 144 Schiff-base intermediate with substrate
 MOD_RES 2 2 N-acetylserine.  

Keyword

 Acetylation; Complete proteome; Pentose shunt; Reference proteome; Schiff base; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 335 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; ISS:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IDA:SGD.
 GO:0006098; P:pentose-phosphate shunt; IMP:SGD. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR001585; Transaldolase.
 IPR004730; Transaldolase_1.
 IPR018225; Transaldolase_AS. 

Pfam

 PF00923; Transaldolase 

SMART

  

PROSITE

 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 

PRINTS