| Tag | Content |
|---|
| CPLM ID | CPLM-005821 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribonuclease T |
Protein Synonyms/Alias | Exoribonuclease T; RNase T |
Gene Name | rnt |
Gene Synonyms/Alias | b1652; JW1644 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 101 | EALHEIFKVVRKGIK | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases. |
Sequence Annotation | DOMAIN 19 194 Exonuclease. |
Keyword | 3D-structure; Complete proteome; Exonuclease; Hydrolase; Nuclease; Reference proteome; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 215 AA |
Protein Sequence | MSDNAQLTGL CDRFRGFYPV VIDVETAGFN AKTDALLEIA AITLKMDEQG WLMPDTTLHF 60
HVEPFVGANL QPEALAFNGI DPNDPDRGAV SEYEALHEIF KVVRKGIKAS GCNRAIMVAH 120
NANFDHSFMM AAAERASLKR NPFHPFATFD TAALAGLALG QTVLSKACQT AGMDFDSTQA 180
HSALYDTERT AVLFCEIVNR WKRLGGWPLS AAEEV 215 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0008408; F:3'-5' exonuclease activity; IGI:EcoCyc. GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:HAMAP. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0042780; P:tRNA 3'-end processing; IGI:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |