CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027093
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cb1-812 
Protein Synonyms/Alias
 Thiopurine S-methyltransferase 
Gene Name
 Tpmt 
Gene Synonyms/Alias
 Ocln 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
45EQGHQLLKKHFDTFLacetylation[1]
53KHFDTFLKGQSGLRVacetylation[1]
159WSRANIGKFDRIWDRacetylation[1]
219YVPDAELKKLFGTKCacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 259 AA 
Protein Sequence
MSLGIKEHPD AEVQKNRVLT LDDWQDKWVT RHIAFHQEQG HQLLKKHFDT FLKGQSGLRV 60
FFPLCGKAIE MKWFADRGHT VVGVEISEIG IREFFAEQNL SYTEEPLTEI AGAKVFKVCT 120
DYEFFREHFL ILLQHFRPSQ IKRNNLSLPS LWSRANIGKF DRIWDRGALV AVNPGDRDRY 180
ADIILSLLRK GYHYLLVVLS YDPTKHTGPP FYVPDAELKK LFGTKCNMQC LEEVDALEER 240
HKTWGVDYFF EKLYLLTEK 259 
Gene Ontology
 GO:0008119; F:thiopurine S-methyltransferase activity; IEA:Compara.
 GO:0033574; P:response to testosterone stimulus; IEP:RGD. 
Interpro
 IPR025835; Thiopurine_S-MeTrfase.
 IPR008854; TPMT. 
Pfam
 PF05724; TPMT 
SMART
  
PROSITE
  
PRINTS