UniProt Accession

 CIP1_HUMAN; Q9NPC3 

Genbank Protein ID

 AF216381; AL161994; AK026233; BX161423; BX161424; BX247978; BC000369; BC001218; BC004435 

Genbank Nucleotide ID

 AAF36386.1; CAB82326.1; BAB15403.1; CAD61896.1; CAD61897.1; CAD62312.1; AAH00369.1; AAH01218.1; AAH04435.1 

Protein Name

 E3 ubiquitin-protein ligase CCNB1IP1 

Protein Synonyms/Alias

 Cyclin-B1-interacting protein 1; Human enhancer of invasion 10 

Gene Name

 CCNB1IP1 

Gene Synonyms/Alias

 C14orf18; HEI10 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
132	YTQQIQSKDVELTSM	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. 

Sequence Annotation

 ZN_FING 4 51 RING-type; atypical.  

Keyword

 Chromosome; Coiled coil; Complete proteome; Ligase; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 277 AA 

Protein Sequence

Gene Ontology

 GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0001825; P:blastocyst formation; IEA:Compara.
 GO:0051026; P:chiasma assembly; IEA:Compara.
 GO:0035265; P:organ growth; IEA:Compara.
 GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
 GO:0007286; P:spermatid development; IEA:Compara. 

Interpro

  

Pfam

  

SMART

  

PROSITE

 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 

PRINTS