CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024968
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ROBO2 isoform b 
Protein Synonyms/Alias
 Roundabout homolog 2 
Gene Name
 Robo2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
888YWRRKKRKGLSNYAVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1508 AA 
Protein Sequence
MNPLMFTLLL LFGFLCIQID GSRLRQEDFP PRIVEHPSDV IVSKGEPTTL NCKAEGRPTP 60
TIEWYKDGER VETDKDDPRS HRMLLPSGSL FFLRIVHGRR SKPDEGSYVC VARNYLGEAV 120
SRNASLEVAL LRDDFRQNPT DVVVAAGEPA ILECQPPRGH PEPTIYWKKD KVRIDDKEER 180
ISIRGGKLMI SNTRKSDAGM YTCVGTNMVG ERDSDPAELT VFERPTFLRR PINQVVLEEE 240
AVEFRCQVQG DPQPTVRWKK DDADLPRGRY DIKDDYTLRI KKAMSTDEGT YVCIAENRVG 300
KVEASATLTV RAPPQFVVRP RDQIVAQGRT VTFPCETKGN PQPAVFWQKE GSQNLLFPNQ 360
PQQPNSRCSV SPTGDLTITN IQRSDAGYYI CQALTVAGSI LAKAQLEVTD VLTDRPPPII 420
LQGPINQTLA VDGTALLKCK ATGEPLPVIS WLKEGFTFLG RDPRATIQDQ GTLQIKNLRI 480
SDTGTYTCVA TSSSGETSWS AVLDVTESGA TISKNYDMND LPGPPSKPQV TDVSKNSVTL 540
SWQPGTPGVL PASAYIIEAF SQSVSNSWQT VANHVKTTLY TVRGLRPNTI YLFMVRAINP 600
QGLSDPSPMS DPVRTQDISP PAQGVDHRQV QKELGDVVVR LHNPVVLTPT TVQVTWTVDR 660
QPQFIQGYRV MYRQTSGLQA STVWQNLDAK VPTERSAVLV NLKKGVTYEI KVRPYFNEFQ 720
GMDSESKTVR TTEEAPSAPP QSVTVLTVGS HNSTSISVSW DPPPADHQNG IIQEYKIWCL 780
GNETRFHINK TVDAAIRSVV IGGLFPGIQY RVEVAASTSA GVGVKSEPQP IIIGGRNEVV 840
ITENNNSITE QITDVVKQPA FIAGIGGACW VILMGFSIWL YWRRKKRKGL SNYAVTFQRG 900
DGGLMSNGSR PGLLNAGDPN YPWLADSWPA TSLPVNNSNS GPNEIGNFGR GDVLPPVPGQ 960
GDKTATMLSD GAIYSSIDFT TKTTYNSSSQ ITQATPYATT QILHSNSIHE LAVDLPDPQW 1020
KSSVQQKTDL MGFGYSLPDQ NKGNNALLYI PDYRLAEGLS NRMPHNQSQD FSTTSSHNSS 1080
ERSGSLSGGK GGKKKKTKNS SKAQKNNGST WANVPLPPPP VQPLPGTELG HYAAEQENGY 1140
DSDSWCPPLP VQTYLHQGME DELEEDEDRV PTPPVRGVAS SPAISFGQQS TATLTPSPRE 1200
EMQPMLQAHL DELTRAYQFD IAKQTWHIQS NTPPPQPPAP PLGYVSGALI SDLETDVPDE 1260
DADDEEEPLE IPRPLRALDQ TPGSSMDNLD SSVTGKAFSS SQRQRPTSPF STDSNTSAAQ 1320
NQSQRPRPTK KHKGGRMDPQ PVLPHRREGM PDDLPPPPDP PPGQGLRQQI GLSQHSGNVE 1380
NSTERKGSSL ERQQAANLED TKSSLDCPAK TVLEWQRQTQ DWINSTERQE ETRKAPHKQG 1440
VGSEESLVPY SKPSFPSPGG HSSSGTSSSK GSTGPRKADV LRGSHQRNAN DLLDIGYVGS 1500
NSQGQFTE 1508 
Gene Ontology
 GO:0030673; C:axolemma; IDA:MGI.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0061364; P:apoptotic process involved in luteolysis; IEA:Compara.
 GO:0007411; P:axon guidance; IMP:MGI.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0032870; P:cellular response to hormone stimulus; IEA:Compara.
 GO:0007156; P:homophilic cell adhesion; IEA:Compara.
 GO:0001656; P:metanephros development; IMP:MGI.
 GO:0050925; P:negative regulation of negative chemotaxis; IEA:Compara.
 GO:0050772; P:positive regulation of axonogenesis; IEA:Compara.
 GO:0001657; P:ureteric bud development; IEA:Compara. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2. 
Pfam
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS