UniProt Accession

 ILV6_YEAST; P25605; D6VR03; P87009 

Genbank Protein ID

 X59720; BK006937 

Genbank Nucleotide ID

 CAA42350.1; DAA07472.1 

Protein Name

 Acetolactate synthase small subunit, mitochondrial 

Protein Synonyms/Alias

 Acetohydroxy-acid synthase small subunit; AHAS; ALS 

Gene Name

 ILV6 

Gene Synonyms/Alias

 YCL009C; YCL9C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
202	LVAEIREKQFHPANL	acetylation	[1]
218	ASEVLRLKHEHLNDI	acetylation	[1]
284	ALPRTPLKTSTEEAA	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Stimulates activity of the acetolactate synthase catalytic subunit ILV2 seven- to tenfold and confers sensitivity to inhibition by valine and activation by ATP. 

Sequence Annotation

 DOMAIN 79 159 ACT.  

Keyword

 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Direct protein sequencing; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 309 AA 

Protein Sequence

Gene Ontology

 GO:0005948; C:acetolactate synthase complex; IDA:SGD.
 GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
 GO:0003984; F:acetolactate synthase activity; IDA:SGD.
 GO:0016597; F:amino acid binding; IEA:InterPro.
 GO:0030234; F:enzyme regulator activity; IDA:SGD.
 GO:0009082; P:branched-chain amino acid biosynthetic process; IDA:SGD.
 GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0009099; P:valine biosynthetic process; IEA:UniProtKB-UniPathway. 

Interpro

 IPR004789; Acetalactate_synth_ssu.
 IPR019455; Acetolactate_synth_ssu_C.
 IPR002912; ACT_dom. 

Pfam

 PF01842; ACT
 PF10369; ALS_ss_C 

SMART

  

PROSITE

 PS51671; ACT 

PRINTS