CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039814
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myotubularin 
Protein Synonyms/Alias
  
Gene Name
 MTM1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19YGLDITCKDMRNLRFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 416 AA 
Protein Sequence
MGGATSRGEN SYGLDITCKD MRNLRFALKQ EGHSRRDMFE ILTRYAFPLA HSLPLFAFLN 60
EEKFNVDGWT VYNPVEEYRR QGLPNHHWRI TFINKCYELC DTYPALLVVP YRASDDDLRR 120
VATFRSRNRI PVLSWIHPEN KTVIVRCSQP LVGMSGKRNK DDEKYLDVIR ETNKQISKLT 180
IYDARPSVNA VANKATGGGY ESDDAYHNAE LFFLDIHNIH VMRESLKKVK DIVYPNVEES 240
HWLSSLESTH WLEHIKLVLT GAIQVADKVS SGKSSVLVHC SDGWDRTAQL TSLAMLMLDS 300
FYRSIEGFEI LVQKEWISFG HKFASRIGHG DKNHTDADRS PIFLQFIDCV WQMSKQFPTA 360
FEFNEQFLII ILDHLYSCRF GTFLFNCESA RERQALHFLS LSLCRRLQKG LFLYGH 416 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR010569; Myotub-related.
 IPR017906; Myotubularin_phosphatase_dom.
 IPR011993; PH_like_dom.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF06602; Myotub-related
 PF00102; Y_phosphatase 
SMART
  
PROSITE
 PS51339; PPASE_MYOTUBULARIN
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2 
PRINTS