CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033755
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Snurportin-1 
Protein Synonyms/Alias
  
Gene Name
 SNUPN 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
94RRLLELQKSKRLDYVubiquitination[1]
186GSTSAYTKSGYCVNRubiquitination[1, 2, 3]
263EEEGLGEKTKLNPFKubiquitination[1, 4]
265EGLGEKTKLNPFKFVubiquitination[1]
270KTKLNPFKFVGLKNFubiquitination[1, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [5] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MPLHSSLGNK SETLSQKKNN NNKEKTKRNS RNPPRTALKE GKMEELSQAL ASSFSVSQDL 60
NSTAAPHPRL SQYKSKYSSL EQSERRRRLL ELQKSKRLDY VNHARRLAED DWTGMESEEE 120
NKKDDEEMDI DTVKKLPKHY ANQLMLSEWL IDVPSDLGQE WIVVVCPVGK RALIVASRGS 180
TSAYTKSGYC VNRFSSLLPG GNRRNSTAKD YTILDCIYNE VNQTYYVLDV MCWRGHPFYD 240
CQTDFRFYWM HSKLPEEEGL GEKTKLNPFK FVGLKNFPCT PESLCDVLSM DFPFEVDGLL 300
FYHKQTHYSP GSTPLVGWLR PYMVSDVLGV AVPAGPLTTK PDYAGHQLQQ IMEHKKSQKE 360
GMKEKLTHKA SENGHYELEH LSTPKLKGSS HSPDHPGCLM EN 402 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006606; P:protein import into nucleus; IEA:InterPro.
 GO:0061015; P:snRNA import into nucleus; IEA:InterPro. 
Interpro
 IPR002652; Importin-a_IBB.
 IPR017336; Snurportin-1.
 IPR024721; Snurportin-1_N. 
Pfam
 PF11538; Snurportin1 
SMART
  
PROSITE
 PS51214; IBB 
PRINTS