CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007987
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor 1 
Protein Synonyms/Alias
 eIF1; Protein translation factor SUI1 homolog 
Gene Name
 Eif1 
Gene Synonyms/Alias
 Sui1; Sui1-rs1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
91QLQGDQRKNICQFLIacetylation[1]
109LAKDDQLKVHGF***acetylation[1, 2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
 Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA (By similarity). 
Sequence Annotation
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 9 9 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Initiation factor; Phosphoprotein; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 113 AA 
Protein Sequence
MSAIQNLHSF DPFADASKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI ADDYDKKKLV 60
KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLIEI GLAKDDQLKV HGF 113 
Gene Ontology
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
 GO:0009048; P:dosage compensation by inactivation of X chromosome; IMP:MGI. 
Interpro
 IPR005874; SUI1_euk.
 IPR001950; TIF_SUI1. 
Pfam
 PF01253; SUI1 
SMART
  
PROSITE
 PS50296; SUI1 
PRINTS