CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033358
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin-like protein KIF26A 
Protein Synonyms/Alias
  
Gene Name
 KIF26A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
134AGPDGLSKAWGRGGVubiquitination[1]
173FFIRAMQKLSLASKRubiquitination[1]
181LSLASKRKKPHPPPPubiquitination[1]
256AEAMSFLKVDPRKKQubiquitination[1]
436LRAPTAEKAAFYLDAubiquitination[1]
1418RGTVMGTKQALRAAHubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1743 AA 
Protein Sequence
MHLLQAPASH EDLDAPHGGP SLAPPSTTTS SRDTPGPAGP AGRQPGRAGP DRTKGLAWSP 60
GPSVQVSVAP AGLGGALSTV TIQAQQCLEG MWSVSRVNSF LPPACLAEAA VAAVAVADTV 120
RECPPVAGPD GLSKAWGRGG VCTSALVTPT PGSVGGSTGP SAAASFFIRA MQKLSLASKR 180
KKPHPPPPPA TRGTSTYPTD FSGVLQLWPP PAPPCLLRAA SKTKDNPGSI GKVKVMLRIW 240
PAQGAQRSAE AMSFLKVDPR KKQVILYDPA AGPPGSAGPR RAATAAVPKM FAFDAVFPQD 300
SEQAEVCSGT VADVLQSVVS GADGCIFSFG HMSLGKSYTM IGKDSSPQSL GIVPCAISWL 360
FRLIEERRER TGTRFSVRVS AVEVCGRDQS LRDLLAEVAP GSLQDTQSPG VYLREDPVCG 420
AQLQNQSELR APTAEKAAFY LDAALAARST SRAGCGEDAR RSSHMLFTLH VYQYRMEKCG 480
RGGMSGGRSR LHLIDLGSCE AAAGRAGEAA GGPLCLSLSA LGSVILALVN GAKHVPYRDH 540
RLTMLLRESL ATAGCRTTMI AHVSDAPAQH AETLSTVQLA ARIHRLRRKK AKYASSSSGG 600
ESSCEEGRAR RPPHLRPFHP RTVALDPDRT PPCLPGDPDY SSSSEQSCDT VIYVGPGGAA 660
LSDRELTDNE GPPDFVPIIP ALSRHRPSKG PRDADHFRCS TFAELQERLE CMDGNEGPSG 720
GPGGTDGAQA SPARGGRKPS PPEAASPRKA VGTPMAASTP RGSSGPDTHQ GTPEPCKAIV 780
WGDQREDSSA WPELLVPEKA AVSGGRRPLP SPAPPPPQLL EACRAPEEPG GGGTDGVART 840
PPVGMSGQVA GSPMLPGATC PRLAAGSRCP ERGLLTTTVT LQRPVELNGE DELVFTVVEE 900
LSLGALAGAG RPTSLASFDS DCSLRALASG SRPVSIISSI NDEFDAYTSQ APEGGPLEGA 960
AWAGSSHGSS ISSWLSEVSV CTADSRDPTP QPRFSPDSLA GLDPGGPPAL DGSLGDGSSG 1020
FLGPDRPDSP GPTWGPCPGE VAAVAPSRPG REPQAGPSRW ASAAQTIHSS LPRKPRTASA 1080
TTRVGCARLG QSPPGRGGLF EDPWLLRVGE CDTQAASAGR APSPTLGSPR LPEAQVMLAC 1140
AQRVVDGCEV AARAARRPEA VARIPPLRRG ATTLGVTTPA VSWGDAPTEV VACSGSLKAS 1200
PTSKKGLAPK AGFLPRPSGA APPAPPTRKS SLEQRSSPAS APPHAVNPAR VGAAAVLRGE 1260
EEPRPSSRAD HSVPRATSSL KARASKVEAA HRLAGHASLE RYEGLAHSSS KGREAPGRPP 1320
RAVPKLGVPP SSPTHGPAPA CRSGAAKAVG APKPPVGGGK GRGLVAGGSR ALGPSVKLST 1380
ASVTGRSPGG PVAGPRAAPR AGPSVGAKAG RGTVMGTKQA LRAAHSRVHE LSASGAPGRG 1440
GSSWGSADSD SGHDSGVNVG EERPPTGPAL PSPYSKVTAP RRPQRYSSGH GSDNSSVLSG 1500
ELPPAMGRTA LFHHSGGSSG YESLRRDSEA TGSASSAPDS MSESGAASPG ARTRSLKSPK 1560
KRATGLQRRR LIPAPLPDTT ALGRKPSLPG QWVDLPPPLA GSLKEPFEIK VYEIDDVERL 1620
QRPRPTPREA PTQGLACVST RLRLAERRQQ RLREVQAKHK HLCEELAETQ GRLMLEPGRW 1680
LEQFEVDPEL EPESAEYLAA LERATAALEQ CVNLCKAHVM MVTCFDISVA ASAAIPGPQE 1740
VDV 1743 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0048484; P:enteric nervous system development; IEA:Compara.
 GO:0007018; P:microtubule-based movement; IEA:InterPro.
 GO:0009968; P:negative regulation of signal transduction; IEA:Compara.
 GO:0001560; P:regulation of cell growth by extracellular stimulus; IEA:Compara. 
Interpro
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.