CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040068
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable phospholipid-transporting ATPase IIB 
Protein Synonyms/Alias
  
Gene Name
 ATP9B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32ESRYTQAKLSMHDRSubiquitination[1]
218GIEGKEGKQASLAADubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Magnesium; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 457 AA 
Protein Sequence
MAREGLRTLV VAKKALTEEQ YQDFESRYTQ AKLSMHDRSL KVAAVVESLE REMELLCLTG 60
VEDQLQADVR PTLEMLRNAG IKIWMLTGDK LETATCIAKS SHLVSRTQDI HIFRQVTSRG 120
EAHLELNAFR RKHDCALVIS GDSLEVCLKY YEHEFVELAC QCPAVVCCRC SPTQKARIVT 180
LLQQHTGRRT CAIGDGGNDV SMIQAADCGI GIEGKEGKQA SLAADFSITQ FRHIGRLLMV 240
HGRNSYKRSA ALGQFVMHRG LIISTMQAVF SSVFYFASVP LYQGFLMVGY ATIYTMFPVF 300
SLVLDQDVKP EMAMLYPELY KDLTKGRSLS FKTFLIWVLI SIYQGGILMY GALVLFESEF 360
VHVVAISFTA LILTELLMVA LTVRTWHWLM VVAEFLSLGC YVSSLAFLNE YFDVAFITTV 420
TFLWKVSAIT VVSCLPLYVL KYLRRKLSPP SYCKLAS 457 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004012; F:phospholipid-translocating ATPase activity; IEA:InterPro. 
Interpro
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR006539; ATPase_P-typ_Plipid-transp.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00702; Hydrolase 
SMART
  
PROSITE
  
PRINTS
 PR00119; CATATPASE.