CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030818
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MAP1S light chain 
Protein Synonyms/Alias
 cDNA FLJ55328, highly similar to Homo sapiens BPY2 interacting protein 1 (BPY2IP1), mRNA 
Gene Name
 MAP1S 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47ATFSSIVKGQRSLHHubiquitination[1, 2]
70VLLNPSDKSLYDELRubiquitination[2, 3, 4]
251NPKSSFWKLVRHLDRubiquitination[2]
354SRGPVPAKPTVLFEKubiquitination[2, 3, 5]
361KPTVLFEKMGVGRLDubiquitination[2, 3, 4]
974LDALLASKQHWDRDLubiquitination[2, 3, 5, 6]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [6] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1033 AA 
Protein Sequence
MAGMIDRFSP ANTGIRSWDV DPGVCNLDEQ LKVFVSRHSA TFSSIVKGQR SLHHRGDNLE 60
TLVLLNPSDK SLYDELRNLL LDPASHKLLV LAGPCLEETG ELLLQTGGFS PHHFLQVLKD 120
REIRDILATT PPPVQPPILT ITCPTFGDWA QLAPAVPGLQ GALRLQLRLN PPAQLPNSEG 180
LCEFLEYVAE SLEPPSPFEL LEPPTSGGFL RLGRPCCYIF PGGLGDAAFF AVNGFTVLVN 240
GGSNPKSSFW KLVRHLDRVD AVLVTHPGAD SLPGLNSLLR RKLAERSEVA AGGGSWDDRL 300
RRLISPNLGV VFFNACEAAS RLARGEDEAE LALSLLAQLG ITPLPLSRGP VPAKPTVLFE 360
KMGVGRLDMY VLHPPSAGAE RTLASVCALL VWHPAGPGEK VVRVLFPGCT PPACLLDGLV 420
RLQHLRFLRE PVVTPQDLEG PGRAESKESV GSRDSSKREG LLATHPRPGQ ERPGVARKEP 480
ARAEAPRKTE KEAKTPRELK KDPKPSVSRT QPREVRRAAS SVPNLKKTNA QAAPKPRKAP 540
STSHSGFPPV ANGPRSPPSL RCGEASPPSA ACGSPASQLV ATPSLELGPI PAGEEKALEL 600
PLAASSIPRP RTPSPESHRS PAEGSERLSL SPLRGGEAGP DASPTVTTPT VTTPSLPAEV 660
GSPHSTEVDE SLSVSFEQVL PPSAPTSEAG LSLPLRGPRA RRSASPHDVD LCLVSPCEFE 720
HRKAVPMAPA PASPGSSNDS SARSQERAGG LGAEETPPTS VSESLPTLSD SDPVPLAPGA 780
ADSDEDTEGF GVPRHDPLPD PLKVPPPLPD PSSICMVDPE MLPPKTARQT ENVSRTRKPL 840
ARPNSRAAAP KATPVAAAKT KGLAGGDRAS RPLSARSEPS EKGGRAPLSR KSSTPKTATR 900
GPSGSASSRP GVSATPPKSP VYLDLAYLPS GSSAHLVDEE FFQRVRALCY VISGQDQRKE 960
EGMRAVLDAL LASKQHWDRD LQVTLIPTFD SVAMHTWYAE THARHQALGI TVLGSNSMVS 1020
MQDDAFPACK VEF 1033 
Gene Ontology
 GO:0005874; C:microtubule; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:InterPro.
 GO:0001578; P:microtubule bundle formation; IEA:InterPro. 
Interpro
 IPR001279; Beta-lactamas-like.
 IPR026074; MAP1.
 IPR027322; MAP1S. 
Pfam
  
SMART
  
PROSITE
  
PRINTS