CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002553
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-ketoacyl-CoA thiolase B, peroxisomal 
Protein Synonyms/Alias
 Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B 
Gene Name
 Acaa1b 
Gene Synonyms/Alias
 Acaa1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
173SRLLENEKARDCLIPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 123 123 Acyl-thioester intermediate (By
 ACT_SITE 377 377 Proton acceptor (By similarity).
 ACT_SITE 408 408 Proton acceptor (By similarity).  
Keyword
 Acyltransferase; Complete proteome; Fatty acid metabolism; Lipid metabolism; Peroxisome; Reference proteome; Transferase; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 424 AA 
Protein Sequence
MHRLQVVLGH LAGRSESSSA LQAAPCSAGF PQASASDVVV VHGRRTPIGR AGRGGFKDTT 60
PDELLSAVLT AVLQDVKLKP ECLGDISVGN VLQPGAGAAM ARIAQFLSGI PETVPLSAVN 120
RQCSSGLQAV ANIAGGIRNG SYDIGMACGV ESMTLSERGN PGNISSRLLE NEKARDCLIP 180
MGITSENVAE RFGISRQKQD AFALASQQKA ASAQSKGCFR AEIVPVTTTV LDDKGDRKTI 240
TVSQDEGVRP STTMEGLAKL KPAFKDGGST TAGNSSQVSD GAAAVLLARR SKAEELGLPI 300
LGVLRSYAVV GVPPDIMGIG PAYAIPAALQ KAGLTVNDID IFEINEAFAS QALYCVEKLG 360
IPAEKVNPLG GAIALGHPLG CTGARQVVTL LNELKRRGRR AYGVVSMCIG TGMGAAAVFE 420
YPGN 424 
Gene Ontology
 GO:0005777; C:peroxisome; IDA:UniProtKB.
 GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:EC.
 GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR002155; Thiolase.
 IPR016039; Thiolase-like.
 IPR016038; Thiolase-like_subgr.
 IPR020615; Thiolase_acyl_enz_int_AS.
 IPR020610; Thiolase_AS.
 IPR020617; Thiolase_C.
 IPR020613; Thiolase_CS.
 IPR020616; Thiolase_N. 
Pfam
 PF02803; Thiolase_C
 PF00108; Thiolase_N 
SMART
  
PROSITE
 PS00098; THIOLASE_1
 PS00737; THIOLASE_2
 PS00099; THIOLASE_3 
PRINTS