| Tag | Content |
|---|
| CPLM ID | CPLM-005637 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-processing protein 45 |
Protein Synonyms/Alias | |
Gene Name | PRP45 |
Gene Synonyms/Alias | FUN20; YAL032C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 287 | QGRDVSEKIILGAAK | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in pre-mRNA splicing. Associated with the spliceosome throughout the splicing reactions, until after the second catalytic step. |
Sequence Annotation | |
Keyword | Complete proteome; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 379 AA |
Protein Sequence | MFSNRLPPPK HSQGRVSTAL SSDRVEPAIL TDQIAKNVKL DDFIPKRQSN FELSVPLPTK 60
AEIQECTART KSYIQRLVNA KLANSNNRAS SRYVTETHQA PANLLLNNSH HIEVVSKQMD 120
PLLPRFVGKK ARKVVAPTEN DEVVPVLHMD GSNDRGEADP NEWKIPAAVS NWKNPNGYTV 180
ALERRVGKAL DNENNTINDG FMKLSEALEN ADKKARQEIR SKMELKRLAM EQEMLAKESK 240
LKELSQRARY HNGTPQTGAI VKPKKQTSTV ARLKELAYSQ GRDVSEKIIL GAAKRSEQPD 300
LQYDSRFFTR GANASAKRHE DQVYDNPLFV QQDIESIYKT NYEKLDEAVN VKSEGASGSH 360
GPIQFTKAES DDKSDNYGA 379 |
Gene Ontology | GO:0071014; C:post-mRNA release spliceosomal complex; IDA:SGD. GO:0071006; C:U2-type catalytic step 1 spliceosome; IDA:SGD. GO:0071007; C:U2-type catalytic step 2 spliceosome; IDA:SGD. GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |