CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040563
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Fryl 
Protein Synonyms/Alias
  
Gene Name
 Fryl 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
30EFAVQAEKKIEVVMAubiquitination[1]
136LVLVEVLKQIPVHPVacetylation[2]
1780SSKNPSIKSADQLATubiquitination[1]
1838FQIFRALKQPLSADTubiquitination[1]
2241YVQSPYWKEALNILKubiquitination[1]
2909LIETLKNKEFVSAVAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3007 AA 
Protein Sequence
MSSITIDPDV KPGEYVIKSL FAEFAVQAEK KIEVVMAEPL EKLLSRSLQR GEDLQFDQLV 60
SSMSSVAEHC LPSLLRTLFD WYRRQNGTDD ESYGYRPRSS TKSKGDEQHR ERDYLLERRD 120
LAVDFIFCLV LVEVLKQIPV HPVPDPLVHE VLNLAFKHFK HKEGYSGTNT GNVHIIADLY 180
AEVIGVLAQS KFQAVRKKFV TELKELRQKE QSPHVVQSVI SLIMGMKFFR VKMYPVEDFE 240
ASFQFMQECA QYFLEVKDKD IKHALAGLFV EILIPVAAAV KNEVNVPCLK NFVEMLYQTT 300
FELSSRKKHS LALYPLITCL LCVSQKQFFL NNWHIFLQNC LSHLKNKDPK MSRVALESLY 360
RLLWVYVIRI KCESNTVTQS RLMSIVSALF PKGSRSVVPR DTPLNIFVKI IQFIAQERLD 420
FAMKEIIFDL LSVGKSTKTF TINPERMNIG LRVFLVIADS LQQKDGDPPM PTTGVILPSG 480
NTLRVKKIFL NKTLTDEEAK VIGMSVYYPQ VRKALDSILR HLDKEVGRPM CMTSVQMSNK 540
EPEDMITGER KPKIDLFRTC IAAIPRLIPD GMSRTDLIEL LARLTIHMDE ELRALAFNTL 600
QALMLDFPDW REDVLSGFVY FIVREVTDVH PTLLDNAVKM LVQLINQWKQ AAQMYNRTQD 660
SQHGIANGGP HPPPLERNPY STVFHVVEGF ALVILCSSRP ATRRLAVSVL REIRALFALL 720
EVPKGDDELA IDVMDRLSPS ILESFIHLTG ADQTTLLYCP SSVDLQTLAD WNSSPISHQF 780
DVISPSHIWI FAHVTQGQDP WIISLSSFLK QENLPKHCST AVSYAWMFAY TRLQLLSPQV 840
DINSPINAKK VNATTSSDSY IGLWRNYLVL CCSAATSPSP SAPAGSVRCS PPETLASTPD 900
SGYSIDSKIV GIPSPSSLFK HIVPMMRSES MEITESLVLG LGRTNPGVFR ELIEELHPII 960
KEALERRPEN MKRRRRRDIL RVQLVRIFEL LADAGVISHS ASGGLDSETH FLNNTLLEYV 1020
DLTRQLLEAE NEKDSDTLKD IRCHFSALVA NIIQNVPVHQ RRSIFPQQSL RHSLFMLFSH 1080
WAGPFSIMFT PLDRYSDRNM QINRHQYCAL KAMSAVLCCG PVADNVGLSS DGYLYKWLDN 1140
ILDSLDKKVH QLGCEAVTLL LELNPDQSSL MYWAVDRCYT GSRRVAAGCF KAIANVFQNR 1200
DYQCDTVMLL NLILFKAADS SRSIYEVAMQ LLQILEPKMF RYAHKLEVQR TDGVLSQLSP 1260
LPHLYSVSYY QLSEELARAY PELTLAIFSE ISQRIQTAHP AGRQAMLHYL LPWMNNIELV 1320
DLKPLPSGRR QDEDEDDSLK DRELMVTSRR WLRGEGWGSP QATAMVLNNL MYMTAKYGDE 1380
LAWSEVENVW TTLADGWPKN LKIILHFLIS ICGVNSEPSL LPYVKKVIVY LGRDKTMQLL 1440
EELVSELQLT DPVSSGVTHM DNPPYYRITS SCKIPSVTSG TTSSSNTMVA PTDGNPDSKA 1500
LKENFEESYV HLDIYGGLNS HLNRQHHRLE SRYSSSSGGS YEEEKSDSMP LYSNWRLKVM 1560
EHNQGEPLPF PPAGGCWSPL VDYVPETASP GLPLHRCNIA VILLTDLIID HSVKVEWGSY 1620
LHLLLHAIFI GFDHCHPEVY EHCKRLLLHL LIVMGPNSDI RTVASVLLRD KEFNEPRVLT 1680
VKQTAHSDYT FTAGINDFTP DYQPSPMTDS GLSSSSTSSS ISLGNNSAAI SHLHTTLLGE 1740
VDLSVEQDGK VKTLMEFITS RKRGPLWNHE DVSSKNPSIK SADQLATFLK HVVSVFKQSN 1800
AEGIHLERHL SEVALQTALS CSSRHYAGRS FQIFRALKQP LSADTLSDVL SRLVETVGDP 1860
GEDAQGFVIE LLLTLESAID TLAETMKHYD LLSALSQSSY HDPVMGNKYA ANRKSTGQLN 1920
LSTSPINSSG HLGCNGDTRS NSLRLSLVGD RRGDRRRSNT LDITDGRINH GGSLARTRSL 1980
SSLREKGVYD TQPPTEPSNL MATIFWIATS LLESDYEYEY LLALRLLSKL LTHLPLDKSE 2040
SREKIENVQS KLKWSNFPGL QQLFLKGFTS VSTQEMTVHL LSQLISVSKH TLVDPSQVSG 2100
FPLNILCLLP HLIQHFDSPT QFCKETASRI AKVCAEEKCP TLVNLAHMMS LYSTHTYSRD 2160
CSNWINVVCR YLHDSFSEAT FSLVTYLAEL LEKGLSSMQQ SLLQIIYSLL SHIDLSAAPV 2220
KQFNLEIIKI IGKYVQSPYW KEALNILKLV VSRSASLVVP NDIPKAYGVD VGSPEISFAK 2280
IFNNVSKELP GKTLDFHFDI SETPIIGNKY GGQHSAAGRN GKAKVIAVTR STSSTSSGST 2340
SNALVPVSWK RPQLSQRRTR EKLMSVLSLC GPESGLPKNP SVVFSSNEDL EVGDQQTSLI 2400
STTEDIIQEE EVAVEDNSSE QQFGVFKDFD FLDVELEDAE GESMDNFNWG VRRRSLDSID 2460
KGDTPSLQEY PCSSSTPSLT LTNQEDTDES SEEEAALTAS QILSRTQMLN SDCVTEDMMP 2520
EHQDLLQSQD SASSNTTEDV LQIRDETPSL EACLDNASSQ LPEGTSSVLK EEHVTAFEDE 2580
GSYVIPDQQD PLVCRGILDL EETDMPEPLA PESYPESICE EDVTLALKEL DERCEEEEAD 2640
FSGLSSQEED EQDGFPEVQT SPLPTPFLSA IIAAFQPMAY EDEEEAWRCH VNQTLSDTDG 2700
SCAVFTFHVF SRLFQTIQRK FGEITKEAVG FLGESLQRIG TKFKSSLEVM MACSECPTVF 2760
VDAETLMACG LLETLKFGVL ELQEHLDTYT TKREAAEQWL DNCKRTFGAN EDIYRMNTNA 2820
HELELCRRLY RLHFQLLLLF QAYCKLINQV NTIKNEAEVI NMSEELAQLE GILKEAEAAS 2880
ENEEIDISKA AQTTIETAIH SLIETLKNKE FVSAVAQVKA FRTLWPNDIF GSCDDDPVQT 2940
LLHIYFHHQT LGQTGSFAVI SSNLDMSEAN CKLMELNLEI RESLRTVQSY PLLAQTKPVG 3000
NMTSTGF 3007 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR025614; Cell_morpho_N.
 IPR025481; Cell_Morphogen_C. 
Pfam
 PF14225; MOR2-PAG1_C
 PF14222; MOR2-PAG1_N 
SMART
  
PROSITE
  
PRINTS