CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023740
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 rRNA-processing protein FCF1 homolog 
Protein Synonyms/Alias
  
Gene Name
 FCF1 
Gene Synonyms/Alias
 C14orf111; CGI-35 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
137ERLPCTHKGTYADDCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly (By similarity). 
Sequence Annotation
 DOMAIN 67 166 PINc.  
Keyword
 Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MGKQKKTRKY ATMKRMLSLR DQRLKEKDRL KPKKKEKKDP SALKEREVPQ HPSCLFFQYN 60
TQLGPPYHIL VDTNFINFSI KAKLDLVQSM MDCLYAKCIP CITDCVMAEI EKLGQKYRVA 120
LRIAKDPRFE RLPCTHKGTY ADDCLVQRVT QHKCYIVATV DRDLKRRIRK IPGVPIMYIS 180
NHRYNIERMP DDYGAPRF 198 
Gene Ontology
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR006984; DUF652.
 IPR006596; PINc_nuc-bd. 
Pfam
 PF04900; Fcf1 
SMART
 SM00670; PINc 
PROSITE
  
PRINTS