CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033750
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Inosine-5'-monophosphate dehydrogenase 1 
Protein Synonyms/Alias
  
Gene Name
 IMPDH1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
150VGDVLEAKMRHGFSGubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MEGPLTPPPL QGGGAAAVPE PGARQHPGHE TAAQRYSARL LQAGYEPESD FLILPGFIDF 60
IADEVDLTSA LTRKITLKTP LISSPMDTVT EADMAIAMAL MGGIGFIHHN CTPEFQANEV 120
RKVKKFEQGF ITDPVVLSPS HTVGDVLEAK MRHGFSGIPI TETGTMGSKL VGIVTSRDID 180
FLAEKDHTTL LSEVMTPRIE LVVAPAGVTL KEANEILQRS KKGKLPIVND CDELVAIIAR 240
TDLKKNRDYP LASKDSQKQL LCGAAVGTRE DDKYRLDLLT QAGVDVIVL 289 
Gene Ontology
 GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
 GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR000644; Cysta_beta_synth_core.
 IPR005990; IMP_DH.
 IPR001093; IMP_DH_GMPRt. 
Pfam
 PF00571; CBS
 PF00478; IMPDH 
SMART
 SM00116; CBS 
PROSITE
 PS51371; CBS 
PRINTS