CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006226
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc-regulated transporter 1 
Protein Synonyms/Alias
 High-affinity zinc transport protein ZRT1 
Gene Name
 ZRT1 
Gene Synonyms/Alias
 YGL255W; NRC376 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
167DHTHDEIKDTVVRNTubiquitination[1]
195ANGSHDTKNGVEYYEubiquitination[2, 3]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [3] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269
Functional Description
 High-affinity zinc transport protein. 
Sequence Annotation
 REGION 232 233 Heavy metals binding (By similarity).  
Keyword
 Complete proteome; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
MSNVTTPWWK QWDPSEVTLA DKTPDDVWKT CVLQGVYFGG NEYNGNLGAR ISSVFVILFV 60
STFFTMFPLI STKVKRLRIP LYVYLFAKYF GSGVIVATAF IHLMDPAYGA IGGTTCVGQT 120
GNWGLYSWCP AIMLTSLTFT FLTDLFSSVW VERKYGLSHD HTHDEIKDTV VRNTAAVSSE 180
NDNENGTANG SHDTKNGVEY YEDSDATSMD VVQSFQAQFY AFLILEFGVI FHSVMIGLNL 240
GSVGDEFSSL YPVLVFHQSF EGLGIGARLS AIEFPRSKRW WPWALCVAYG LTTPICVAIG 300
LGVRTRYVSG SYTALVISGV LDAISAGILL YTGLVELLAR DFIFNPQRTK DLRELSFNVI 360
CTLFGAGIMA LIGKWA 376 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IMP:SGD.
 GO:0000006; F:high affinity zinc uptake transmembrane transporter activity; IMP:SGD.
 GO:0006830; P:high-affinity zinc ion transport; IMP:SGD. 
Interpro
 IPR003689; ZIP.
 IPR004698; Zn/Fe_permease_fun/pln. 
Pfam
 PF02535; Zip 
SMART
  
PROSITE
  
PRINTS