CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043108
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Low-density lipoprotein receptor 
Protein Synonyms/Alias
  
Gene Name
 LDLR 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
217FQLDPHTKACKAVGSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; EGF-like domain; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
XLDGSDEASC PVLTCGPASF QCNSSTCIPQ LWACDNDPDC EDGSDEWPQR CRGLYVFQGD 60
SSPCSAFEFH CLSGECIHSS WRCDGGPDCK DKSDEENCAV ATCRPDEFQC SDGNCIHGSR 120
QCDREYDCKD MSDEVGCVNV TLCEGPNKFK CHSGECITLD KVCNMARDCR DWSDEPIKEC 180
DIDECQDPDT CSQLCVNLEG GYKCQCEEGF QLDPHTKACK AVGSIAYLFF TNRHEVRKMT 240
LDRSEYTSLI PNLRNVVALD TEVASNRIYW SDLSQRMICS TQLDRAHGVS SYDTVISRDI 300
QAPDGLAVD 309 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR018097; EGF_Ca-bd_CS.
 IPR023415; LDLR_class-A_CS.
 IPR000033; LDLR_classB_rpt.
 IPR002172; LDrepeatLR_classA_rpt. 
Pfam
 PF07645; EGF_CA
 PF00057; Ldl_recept_a
 PF00058; Ldl_recept_b 
SMART
 SM00179; EGF_CA
 SM00192; LDLa
 SM00135; LY 
PROSITE
 PS00010; ASX_HYDROXYL
 PS01186; EGF_2
 PS01187; EGF_CA
 PS01209; LDLRA_1
 PS50068; LDLRA_2
 PS51120; LDLRB 
PRINTS