| Tag | Content |
|---|
| CPLM ID | CPLM-008698 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative meiotic phospholipase SPO1 |
Protein Synonyms/Alias | Sporulation-specific protein 1 |
Gene Name | SPO1 |
Gene Synonyms/Alias | YNL012W; N2858 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 426 | EEIFSISKDSSRLET | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Regulates spindle pole duplication in meiosis I, but not in mitosis. Required for meiosis I, meiosis II chromosome segregation and spore formation. Binds phosphatidylinositol (4)P mono- and polyphosphates. |
Sequence Annotation | DOMAIN 24 631 PLA2c.
REGION 24 67 Required for lipid-binding and function
CARBOHYD 233 233 N-linked (GlcNAc...) (Potential).
CARBOHYD 293 293 N-linked (GlcNAc...) (Potential).
CARBOHYD 303 303 N-linked (GlcNAc...) (Potential).
CARBOHYD 500 500 N-linked (GlcNAc...) (Potential).
CARBOHYD 536 536 N-linked (GlcNAc...) (Potential).
CARBOHYD 560 560 N-linked (GlcNAc...) (Potential).
CARBOHYD 563 563 N-linked (GlcNAc...) (Potential).
CARBOHYD 572 572 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endoplasmic reticulum; Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism; Meiosis; Membrane; Nucleus; Reference proteome; Signal; Sporulation; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 631 AA |
Protein Sequence | MQKLLFVFSV LLTVVLATAP FQVQCPSSPL IREAKHELCP EETLYLKKKK IKTKNKLIQF 60
LKSLTEAKFS SKFYKRVLKD PPKIGIAISG GGYRSMLVGT GFISQMNDYG LFEYSDYIAG 120
LSGGSWILMD LVVQNFEVKS LLQEWDLEED LLLGIPEFDI SEEEIVTNAK KEYNDNDLKM 180
KKRQGGSLIT SSSNFYEQIE EIMNSIEEIP EDYMITKRNL NPLARLKKIF FPNNTFTGTD 240
AKIETFKKVL DFYKSLHLKI KPKKMEGFQI SFTDYWGKAI VQRLKKNFDD DPNHSFSFSK 300
LVNSSKKFKE CSVPIPIFVA NCKNGLLSNV IFEFTPFEFG SWENILRLFV KLPYLGSKIV 360
SGKAEKCINN FDDLGFITAT SSSIFNNVLI FIWNLASQSS REAMKALNMV MGIFGLGKEE 420
IFSISKDSSR LETDYAVYQP NPFYLYPEKD NVLTNKNHLY LVDGGEDGEN IPLRTLVIPE 480
RELDVIFVLD SSSDIDNYPN GSKLKRIFEK LDEENVHYQF PNNVKTFTHP IVIGCNATKR 540
TGHDSFLPII IYHANANHGN ASNTSTFKIT YNQSEVSSML PTGRGVFSND YDLYYKNCLG 600
CILTKRTMDR LPRKKKFSPF CLQCFKDYCY S 631 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |