UniProt Accession

 H11_RAT; D4A3K5 

Genbank Protein ID

 AABR06091665; CH474064 

Genbank Nucleotide ID

 EDL86563.1 

Protein Name

 Histone H1.1 

Protein Synonyms/Alias

 Histone H1a 

Gene Name

 Hist1h1a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
17	PASVAPEKPAATKKT	acetylation	[1]
22	PEKPAATKKTRKPAK	acetylation	[1]
65	GVSLAALKKSLAAAG	acetylation	[1]
87	SRIKLGLKSLVNKGT	acetylation	[1]
108	TGAAGSFKLNKKAES	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 H1 histones bind to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. H1 histones are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling (By similarity). 

Sequence Annotation

 DOMAIN 38 111 H15.
 MOD_RES 106 106 Phosphoserine (By similarity).  

Keyword

 Chromosome; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 214 AA 

Protein Sequence

Gene Ontology

 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro.
 GO:0007283; P:spermatogenesis; IEA:Compara. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.