CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030030
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GRIP1-associated protein 1 
Protein Synonyms/Alias
  
Gene Name
 GRIPAP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
104AENTALQKNVAALQEubiquitination[1]
204FCRLQTEKETLFNDSubiquitination[1]
214LFNDSRNKIEELQQRubiquitination[1]
595QDILTNSKSRSGLEEubiquitination[2, 3, 4]
677LAETQQEKWMLEEKVubiquitination[3]
683EKWMLEEKVKHLEVSubiquitination[3]
701MAEDLCRKSAIIETYubiquitination[3]
737SVLRDLVKPGDENLRubiquitination[3]
749NLREMNKKLQNMLEEubiquitination[3]
780QEIVRLSKECVGPPDubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 796 AA 
Protein Sequence
MAQALSEEEF QRMQAQLLEL RTNNYQLSDE LRKNGVELTS LRQKVAYLDK EFSKAQKLCS 60
QMEQLEQENQ QLKEGAAGAG VAQAGPLVDG ELLRLQAENT ALQKNVAALQ ERYGKEAGKF 120
SAVSEGQGDP PGGPAPTVLA PMPLAEVELK WEMEKEEKRL LWEQLQGLES SKQAETSRLQ 180
EELAKLSEKL KKKQESFCRL QTEKETLFND SRNKIEELQQ RKEADHKAQL ARTQKLQQEL 240
EAANQSLAEL RDQRQGERLE HAAALRALQD QVSIQSADAQ EQVEGLLAEN NALRTSLAAL 300
EQIQTAKTQE LNMLREQTTG LAAELQQQQA EYEDLMGQKD DLNSQLQESL RANSRLLEQL 360
QEIGQEKEQL TQELQEARKS AEKRKAMLDE LAMETLQEKS QHKEELGAVR LRHEKEVLGV 420
RARYERELRE LHEDKKRQEE ELRGQIREEK ARTRELETLQ QTVEELQAQV HSMDGAKGWF 480
ERRLKEAEES LQQQQQEQEE ALKQCREQHA AELKGKEEEL QDVRDQLEQA QEERDCHLKT 540
ISSLKQEVKD TVDGQRILEK KGSAALKDLK RQLHLERKRA DKLQERLQDI LTNSKSRSGL 600
EELVLSEMNS PSRTQTGDSS SISSFSYREI LREKESSAVP ARSLSSSPQA QPPRPAELSD 660
EEVAELFQRL AETQQEKWML EEKVKHLEVS SASMAEDLCR KSAIIETYVM DSRIDVSVAA 720
GHTDRSGLGS VLRDLVKPGD ENLREMNKKL QNMLEEQLTK NMHLHKDMEV LSQEIVRLSK 780
ECVGPPDPDL EPGETS 796 
Gene Ontology
  
Interpro
 IPR026204; GRIPAP1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS