UniProt Accession

 Q3TJY1_MOUSE; Q3TJY1 

Genbank Protein ID

 AC161198; AK167242 

Genbank Nucleotide ID

 BAE39364.1 

Protein Name

 Microspherule protein 1 

Protein Synonyms/Alias

  

Gene Name

 Mcrs1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
110	TKRVKKSKQPLQVTK	acetylation	[1, 2, 3]
117	KQPLQVTKDLGRWKP	acetylation	[1, 2, 3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 449 AA 

Protein Sequence

Gene Ontology

 GO:0000123; C:histone acetyltransferase complex; IEA:Compara.
 GO:0031011; C:Ino80 complex; IEA:Compara.
 GO:0071339; C:MLL1 complex; IEA:Compara.
 GO:0046972; F:histone acetyltransferase activity (H4-K16 specific); IEA:Compara.
 GO:0043995; F:histone acetyltransferase activity (H4-K5 specific); IEA:Compara.
 GO:0043996; F:histone acetyltransferase activity (H4-K8 specific); IEA:Compara. 

Interpro

 IPR000253; FHA_dom.
 IPR025999; MCRS_N.
 IPR008984; SMAD_FHA_domain. 

Pfam

 PF00498; FHA
 PF13325; MCRS_N 

SMART

 SM00240; FHA 

PROSITE

 PS50006; FHA_DOMAIN 

PRINTS