CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039368
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myosin-8 
Protein Synonyms/Alias
  
Gene Name
 Myh8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
859EKEMATMKEEFQKTKacetylation[1]
866KEEFQKTKDELAKSEacetylation[1]
871KTKDELAKSEAKRKEacetylation[1]
918CEQLIKNKIQLEAKIacetylation[1]
1266EDQVSELKSKEEEQQacetylation[1]
1908VNLAKFRKLQHELEEacetylation[1]
1929IAESQVNKLRVKSREacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1944 AA 
Protein Sequence
TGSDAEMAIF GEAAPYLRKS EKERIEAQNK PFDAKTSVFV AEPKESYVKS VIQSKEGGKV 60
TVKTESGATL TVKEDQVFPM NPPKYDKIED MAMMTHLHEP GVLYNLKERY AAWMIYTYSG 120
LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE APPHIFSISD NAYQFMLTDR ENQSILITGE 180
SGAGKTVNTK RVIQYFATIA VTGEKKKEES GKMQGTLEDQ IISANPLLEA FGNAKTVRND 240
NSSRFGKFIR IHFGTTGKLA SADIETYLLE KSRVTFQLKA ERSYHIFYQI TSNKKPELIE 300
MLLITTNPYD YAFVSQGEIT VPSIDDQEEL MATDSAIDIL GFSPEEKVSI YKLTGAVMHY 360
GNMKFKQKQR EEQAEPDGTE VADKAAYLQS LNSADLLKAL CYPRVKVGNE YVTKGQTVQQ 420
VYNAVGALAK AVYEKMFLWM VTRINQQLDT KQPRQYFIGV LDIAGFEIFD FNSLEQLCIN 480
FTNEKLQQFF NHHMFVLEQE EYKKEGIEWT FIDFGMDLAA CIELIEKPLG IFSILEEECM 540
FPKATDTSFK NKLYDQHLGK SNNFQKPKPT KGKAEAHFSL IHYAGTVDYN ITGWLDSDAS 600
LLSKQIMLMV GMIAKLGFHW NLPATVSIIS AEDRRGHRGH PVAKSVLYDF YQTGKKSKEN 660
LNKLMTNLRS THPHFVRCII PNETKTPGAM EHELVLHQLR CNGVLEGIRI CRKGFPSRIL 720
YGDFKQRYKV LNASAIPEGQ FIDSKKASEK LLGSIDIDHT QYKFGHTKVF FKAGLLGLLE 780
EMRDEKLAQI ITRTQAVCRG YLMRVEYQKM LLRRESIFCI QYNIRAFMNV KHWPWMKLFF 840
KIKPLLKSAE TEKEMATMKE EFQKTKDELA KSEAKRKELE EKMVTLLKEK NDLQLQVQSE 900
ADSLADAEER CEQLIKNKIQ LEAKIKEVTE RAEDEEEINA ELTAKKRKLE DECSELKKDI 960
DDLELTLAKV EKEKHATENK VKNLTEEMAG LDETIAKLTK EKKALQEAHQ QTLDDLQAEE 1020
DKVNTLTKAK TKLEQQVDDL EGSLEQEKKL RMDLERAKRK LEGDLKLAQE STMDIENDKQ 1080
QLDEKLKKKE FEISNLISKI EDEQAVEIQL QKKIKELQAR IEELEEEIEA ERASRAKAEK 1140
QRSDLSRELE EISERLEEAG GATSAQVELN KKRETEFQKL RRDLEEATLQ HEATSAALRK 1200
KHADSMAELG EQIDNLQRVK QKLEKEKSEL KMEIDDLSSN AEAIAKAKGN LEKMCRTLED 1260
QVSELKSKEE EQQRLINELT AQRARLQTEA GEYSRQLDEK DALVSQLSRS KQASTQQIEE 1320
LKRQLEEETK VSFTRDLNKP SLRRPIYSYL RVCXGQERAE EQEGKAELQR ALSKANSEVA 1380
QWRTKYETDA IQRTEELEEA KKKLAQRLQA AEEHVEAVNA KCASLEKTKQ RLQNEVEDLM 1440
LDVERTNAAC AALDKKQRNF DKVLSEWRQK YEETQAELES CQKESRTLST ELFKVKNAYE 1500
ESLDQLETLR RENKNLQQEI SDLTEQIAEG GKHIHELEKI KKQVEQEKCE IQAALEEAEA 1560
SLEHEEGKIL RIQLELNQVK SEIDRKIAEK DEEIDQLKRN HIRVVETMQS TLDAEIRSRN 1620
DALRVKKKME GDLNEMEIQL NHANRLAAES LRNYRNTQGI LKDTQLHLDD ALRGQEDLKE 1680
QLAIVERRAN LLQAEIEELR ATLEQTERSR KIAEQELLDA SERVQLLHTQ YKFRILPHRP 1740
VLTCTHTVDK PSSPSLHHCV HLHSSFERLQ ASYVLTHIKT KQNKTNPTIP NLLSSNASTL 1800
KMSQVLLCSP KSGKIKRTPS SCPGIRFQVR ELEGEVENEQ KRNAEAVKGL RKHERRVKEL 1860
TYQTEEDRKN VLRLQDLVDK LQAKVKSYKR QAEEAEEQSN VNLAKFRKLQ HELEEAEERA 1920
DIAESQVNKL RVKSREVHTK ISAE 1944 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR015650; Myosin_1/23/4/7/8/13/15.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.