CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044027
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase B-raf 
Protein Synonyms/Alias
  
Gene Name
 BRAF 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
73AYEEYTSKLDALQQRubiquitination[1]
149VRVFLPNKQRTVVPAubiquitination[2]
Reference
 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 194 AA 
Protein Sequence
QALFNGDMEP EAGAGAGAAA SSAADPAIPE EVWNIKQMIK LTQEHIEALL DKFGGEHNPP 60
SIYLEAYEEY TSKLDALQQR EQQLLESLGN GTDFSVSSSA SMDTVTSSSS SSLSVLPSSL 120
SVFQNPTDVA RSNPKSPQKP IVRVFLPNKQ RTVVPARCGV TVRDSLKKAL MMRGLIPECC 180
AVYRIQDGSF LELT 194 
Gene Ontology
 GO:0005057; F:receptor signaling protein activity; IEA:InterPro. 
Interpro
 IPR003116; Raf-like_ras-bd. 
Pfam
 PF02196; RBD 
SMART
 SM00455; RBD 
PROSITE
 PS50898; RBD 
PRINTS