| Tag | Content |
|---|
| CPLM ID | CPLM-021777 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-binding cassette sub-family B member 9 |
Protein Synonyms/Alias | ATP-binding cassette transporter 9; ABC transporter 9 protein; mABCB9; TAP-like protein; TAPL |
Gene Name | Abcb9 |
Gene Synonyms/Alias | Kiaa1520 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 351 | KYYKRLSKEVQSALA | ubiquitination | [1] | | 372 | EETISAMKTVRSFAN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored (By similarity). |
Sequence Annotation | DOMAIN 184 467 ABC transmembrane type-1.
DOMAIN 500 736 ABC transporter.
NP_BIND 535 542 ATP (Potential). |
Keyword | Alternative splicing; ATP-binding; Complete proteome; Lysosome; Membrane; Nucleotide-binding; Peptide transport; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 762 AA |
Protein Sequence | MRLWKAVVVT LAFVSTDVGV TTAIYAFSHL DRSLLEDIRH FNIFDSVLDL WAACLYRSCL 60
LLGATIGVAK NSALGPRRLR ASWLVITLVC LFVGIYAMAK LLLFSEVRRP IRDPWFWALF 120
VWTYISLAAS FLLWGLLATV RPDAEALEPG NEGFHGEGGA PAEQASGATL QKLLSYTKPD 180
VAFLVAASFF LIVAALGETF LPYYTGRAID SIVIQKSMDQ FTTAVVVVCL LAIGSSLAAG 240
IRGGIFTLVF ARLNIRLRNC LFRSLVSQET SFFDENRTGD LISRLTSDTT MVSDLVSQNI 300
NIFLRNTVKV TGVVVFMFSL SWQLSLVTFM GFPIIMMVSN IYGKYYKRLS KEVQSALARA 360
STTAEETISA MKTVRSFANE EEEAEVFLRK LQQVYKLNRK EAAAYMSYVW GSGLTLLVVQ 420
VSILYYGGHL VISGQMSSGN LIAFIIYEFV LGDCMESVGS VYSGLMQGVG AAEKVFEFID 480
RQPTMVHDGS LAPDHLEGRV DFENVTFTYR TRPHTQVLQN VSFSLSPGKV TALVGPSGSG 540
KSSCVNILEN FYPLQGGRVL LDGKPIGAYD HKYLHRVISL VSQEPVLFAR SITDNISYGL 600
PTVPFEMVVE AAQKANAHGF IMELQDGYST ETGEKGAQLS GGQKQRVAMA RALVRNPPVL 660
ILDEATSALD AESEYLIQQA IHGNLQRHTV LIIAHRLSTV ERAHLIVVLD KGRVVQQGTH 720
QQLLAQGGLY AKLVQRQMLG LEHPLDYTAS HKEPPSNTEH KA 762 |
Gene Ontology | GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. GO:0005764; C:lysosome; ISO:MGI. GO:0005886; C:plasma membrane; IBA:RefGenome. GO:0042825; C:TAP complex; IBA:RefGenome. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0042288; F:MHC class I protein binding; IBA:RefGenome. GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome. GO:0042605; F:peptide antigen binding; IBA:RefGenome. GO:0046978; F:TAP1 binding; IBA:RefGenome. GO:0046979; F:TAP2 binding; IBA:RefGenome. GO:0046980; F:tapasin binding; IBA:RefGenome. GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |