| Tag | Content |
|---|
| CPLM ID | CPLM-019667 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium/hydrogen exchanger 7 |
Protein Synonyms/Alias | Na(+)/H(+) exchanger 7; NHE-7; Solute carrier family 9 member 7 |
Gene Name | SLC9A7 |
Gene Synonyms/Alias | NHE7 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 709 | DLGMGDQKVSSRGTR | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis. |
Sequence Annotation | |
Keyword | Antiport; Complete proteome; Endosome; Golgi apparatus; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 725 AA |
Protein Sequence | MEPGDAARPG SGRATGAPPP RLLLLPLLLG WGLRVAAAAS ASSSGAAAED SSAMEELATE 60
KEAEESHRQD SVSLLTFILL LTLTILTIWL FKHRRVRFLH ETGLAMIYGL IVGVILRYGT 120
PATSGRDKSL SCTQEDRAFS TLLVNVSGKF FEYTLKGEIS PGKINSVEQN DMLRKVTFDP 180
EVFFNILLPP IIFHAGYSLK KRHFFRNLGS ILAYAFLGTA VSCFIIGNLM YGVVKLMKIM 240
GQLSDKFYYT DCLFFGAIIS ATDPVTVLAI FNELHADVDL YALLFGESVL NDAVAIVLSS 300
SIVAYQPAGL NTHAFDAAAF FKSVGIFLGI FSGSFTMGAV TGVNANVTKF TKLHCFPLLE 360
TALFFLMSWS TFLLAEACGF TGVVAVLFCG ITQAHYTYNN LSVESRSRTK QLFEVLHFLA 420
ENFIFSYMGL ALFTFQKHVF SPIFIIGAFV AIFLGRAAHI YPLSFFLNLG RRHKIGWNFQ 480
HMMMFSGLRG AMAFALAIRD TASYARQMMF TTTLLIVFFT VWIIGGGTTP MLSWLNIRVG 540
VEEPSEEDQN EHHWQYFRVG VDPDQDPPPN NDSFQVLQGD GPDSARGNRT KQESAWIFRL 600
WYSFDHNYLK PILTHSGPPL TTTLPAWCGL LARCLTSPQV YDNQEPLREE DSDFILTEGD 660
LTLTYGDSTV TANGSSSSHT ASTSLEGSRR TKSSSEEVLE RDLGMGDQKV SSRGTRLVFP 720
LEDNA 725 |
Gene Ontology | GO:0000139; C:Golgi membrane; TAS:Reactome. GO:0016021; C:integral to membrane; IDA:UniProtKB. GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. GO:0005802; C:trans-Golgi network; IDA:UniProtKB. GO:0015386; F:potassium:hydrogen antiporter activity; IDA:UniProtKB. GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. GO:0015385; F:sodium:hydrogen antiporter activity; IDA:UniProtKB. GO:0006885; P:regulation of pH; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |