UniProt Accession

 NUDC_MOUSE; O35685; Q3UJS7 

Genbank Protein ID

 X81443; Y15522; AK032673; AK146323; BC011253 

Genbank Nucleotide ID

 CAA57201.1; CAA75677.1; BAC27981.1; BAE27078.1; AAH11253.1 

Protein Name

 Nuclear migration protein nudC 

Protein Synonyms/Alias

 Nuclear distribution protein C homolog; Silica-induced gene 92 protein; SIG-92 

Gene Name

 Nudc 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
68	HHNQLAQKARREKRA	ubiquitination	[1]
197	VSFRLKGKDVVVDIQ	ubiquitination	[1]
251	VHLEKINKMEWWNRL	acetylation	[2]
328	HPEMDFSKAKFN***	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (By similarity). 

Sequence Annotation

 DOMAIN 168 259 CS.
 MOTIF 68 74 Nuclear localization signal (Potential).
 MOD_RES 108 108 Phosphothreonine (By similarity).
 MOD_RES 139 139 Phosphoserine (By similarity).
 MOD_RES 240 240 N6-acetyllysine (By similarity).
 MOD_RES 275 275 Phosphoserine (By similarity).
 MOD_RES 327 327 Phosphoserine (By similarity).  

Keyword

 3D-structure; Acetylation; Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitosis; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 332 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 

Interpro

 IPR007052; CS-like_domain.
 IPR017447; CS_domain.
 IPR008978; HSP20-like_chaperone.
 IPR025934; NudC_N_dom. 

Pfam

 PF04969; CS
 PF14050; Nudc_N 

SMART

  

PROSITE

 PS51203; CS 

PRINTS