CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021802
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Krueppel-like factor 13 
Protein Synonyms/Alias
 Basic transcription element-binding protein 3; BTE-binding protein 3; Erythroid transcription factor FKLF-2; RANTES factor of late activated T-lymphocytes 1; RFLAT-1; Transcription factor BTEB3 
Gene Name
 Klf13 
Gene Synonyms/Alias
 Bteb3; Fklf2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
167DLESPQRKHKCHYAGacetylation[1]
169ESPQRKHKCHYAGCEacetylation[1]
181GCEKVYGKSSHLKAHacetylation[1]
226YRTHTGEKKFSCPICacetylation[1]
227RTHTGEKKFSCPICEacetylation[1]
Reference
 [1] Functional interplay between CBP and PCAF in acetylation and regulation of transcription factor KLF13 activity.
 Song CZ, Keller K, Chen Y, Stamatoyannopoulos G.
 J Mol Biol. 2003 May 30;329(2):207-15. [PMID: 12758070] 
Functional Description
 Transcription factor that activates expression from GC- rich minimal promoter regions, including genes in the cells of the erythroid lineage. 
Sequence Annotation
 ZN_FING 168 192 C2H2-type 1.
 ZN_FING 198 222 C2H2-type 2.
 ZN_FING 228 250 C2H2-type 3.  
Keyword
 Activator; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MAAAAYVDHF AAECLVSMSS RAVVHEPREG PEPRPEGAAA AAPTLPRVDE RRDGKDSASL 60
FVVARILADL NQQAPAPAPA ERREGAAARK ARTPCRLPPA PPAPPPGPEP ASPGQAGAPA 120
APPSPAWSEP EAALEQEPGP AGSGEPGLRQ RGRRGRSRAD LESPQRKHKC HYAGCEKVYG 180
KSSHLKAHLR THTGERPFAC SWQECNKKFA RSDELARHYR THTGEKKFSC PICEKRFMRS 240
DHLTKHARRH ANFHPGMLQR RGGGSRTGSL SDYSRSDASS PTISPASSP 289 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
 GO:0045647; P:negative regulation of erythrocyte differentiation; IMP:BHF-UCL.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0006366; P:transcription from RNA polymerase II promoter; ISS:MGI. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS