UniProt Accession

 DNJA2_RAT; O35824 

Genbank Protein ID

 U95727 

Genbank Nucleotide ID

 AAB64094.1 

Protein Name

 DnaJ homolog subfamily A member 2 

Protein Synonyms/Alias

 RDJ2 

Gene Name

 Dnaja2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
25	GASENELKKAYRKLA	acetylation	[1]
62	EVLSNPEKRELYDRY	ubiquitination	[2]
326	QYRNPFEKGDLYIKF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

  

Sequence Annotation

 DOMAIN 8 70 J.
 REPEAT 143 150 CXXCXGXG motif.
 REPEAT 159 166 CXXCXGXG motif.
 REPEAT 186 193 CXXCXGXG motif.
 REPEAT 202 209 CXXCXGXG motif.
 ZN_FING 130 214 CR-type.
 METAL 143 143 Zinc 1 (By similarity).
 METAL 146 146 Zinc 1 (By similarity).
 METAL 159 159 Zinc 2 (By similarity).
 METAL 162 162 Zinc 2 (By similarity).
 METAL 186 186 Zinc 2 (By similarity).
 METAL 189 189 Zinc 2 (By similarity).
 METAL 202 202 Zinc 1 (By similarity).
 METAL 205 205 Zinc 1 (By similarity).
 MOD_RES 78 78 Phosphoserine (By similarity).
 MOD_RES 409 409 Cysteine methyl ester (By similarity).
 LIPID 409 409 S-farnesyl cysteine (By similarity).  

Keyword

 Chaperone; Complete proteome; Lipoprotein; Membrane; Metal-binding; Methylation; Phosphoprotein; Prenylation; Reference proteome; Repeat; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 412 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:RGD.
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0018885; P:carbon tetrachloride metabolic process; IEP:RGD.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0009408; P:response to heat; IEA:InterPro. 

Interpro

 IPR012724; DnaJ.
 IPR002939; DnaJ_C.
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS.
 IPR008971; HSP40/DnaJ_pept-bd.
 IPR001305; HSP_DnaJ_Cys-rich_dom. 

Pfam

 PF00226; DnaJ
 PF01556; DnaJ_C
 PF00684; DnaJ_CXXCXGXG 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2
 PS51188; ZF_CR 

PRINTS

 PR00625; JDOMAIN.