UniProt Accession

 SEC62_MOUSE; Q8BU14; Q6NX81 

Genbank Protein ID

 AK088093; BC067202 

Genbank Nucleotide ID

 BAC40140.1; AAH67202.1 

Protein Name

 Translocation protein SEC62 

Protein Synonyms/Alias

 Translocation protein 1; TP-1 

Gene Name

 Sec62 

Gene Synonyms/Alias

 Tloc1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
19	QEVGEPSKEEKAVAK	ubiquitination	[1]
22	GEPSKEEKAVAKYLR	ubiquitination	[1]
26	KEEKAVAKYLRFNCP	ubiquitination	[1]
60	VECLLDSKWAKAKKG	ubiquitination	[1]
66	SKWAKAKKGEDALFT	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Required for preprotein translocation (By similarity). 

Sequence Annotation

 MOD_RES 117 117 Phosphoserine.
 MOD_RES 158 158 Phosphothreonine.
 MOD_RES 309 309 Phosphoserine.
 MOD_RES 313 313 Phosphoserine.
 MOD_RES 335 335 Phosphoserine.
 MOD_RES 343 343 Phosphothreonine.
 MOD_RES 345 345 Phosphoserine.
 MOD_RES 353 353 Phosphoserine.
 MOD_RES 356 356 Phosphoserine (By similarity).
 MOD_RES 375 375 Phosphothreonine.  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 398 AA 

Protein Sequence

Gene Ontology

 GO:0016235; C:aggresome; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0008565; F:protein transporter activity; IEA:InterPro. 

Interpro

 IPR004728; Sec62. 

Pfam

 PF03839; Sec62 

SMART

  

PROSITE

  

PRINTS