UniProt Accession

 A2A3R6_HUMAN; A2A3R6 

Genbank Protein ID

 AK291517; AK311861; CH471071 

Genbank Nucleotide ID

 BAF84206.1; BAG34802.1; EAW58641.1 

Protein Name

 40S ribosomal protein S6 

Protein Synonyms/Alias

  

Gene Name

 RPS6 

Gene Synonyms/Alias

 hCG_1741512 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
14	FPATGCQKLIEVDDE	ubiquitination	[1, 2]
58	RISGGNDKQGFPMKQ	ubiquitination	[1, 2]
64	DKQGFPMKQGVLTHG	ubiquitination	[2]
116	LNLVIVKKGEKDIPG	ubiquitination	[2]
143	KRASRIRKLFNLSKE	ubiquitination	[2]
149	RKLFNLSKEDDVRQY	ubiquitination	[2]
211	EEAAEYAKLLAKRMK	ubiquitination	[1, 2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 249 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0042593; P:glucose homeostasis; IEA:Compara.
 GO:0006412; P:translation; IEA:InterPro. 

Interpro

 IPR014401; Ribosomal_S6_euk.
 IPR001377; Ribosomal_S6e.
 IPR018282; Ribosomal_S6e_CS. 

Pfam

 PF01092; Ribosomal_S6e 

SMART

  

PROSITE

 PS00578; RIBOSOMAL_S6E 

PRINTS