CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003445
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UPF0053 inner membrane protein YtfL 
Protein Synonyms/Alias
  
Gene Name
 ytfL 
Gene Synonyms/Alias
 b4218; JW4177 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
401PKRTDSVKFAGYKFEacetylation[1]
406SVKFAGYKFEVVDIDacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
  
Sequence Annotation
 DOMAIN 5 197 DUF21.
 DOMAIN 216 275 CBS 1.
 DOMAIN 282 343 CBS 2.  
Keyword
 CBS domain; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 447 AA 
Protein Sequence
MLNSILVILC LIAVSAFFSM SEISLAASRK IKLKLLADEG NINAQRVLNM QENPGMFFTV 60
VQIGLNAVAI LGGIVGDAAF SPAFHSLFSR YMSAELSEQL SFILSFSLVT GMFILFADLT 120
PKRIGMIAPE AVALRIINPM RFCLYVCTPL VWFFNGLANI IFRIFKLPMV RKDDITSDDI 180
YAVVEAGALA GVLRKQEHEL IENVFELESR TVPSSMTPRE NVIWFDLHED EQSLKNKVAE 240
HPHSKFLVCN EDIDHIIGYV DSKDLLNRVL ANQSLALNSG VQIRNTLIVP DTLTLSEALE 300
SFKTAGEDFA VIMNEYALVV GIITLNDVMT TLMGDLVGQG LEEQIVARDE NSWLIDGGTP 360
IDDVMRVLDI DEFPQSGNYE TIGGFMMFML RKIPKRTDSV KFAGYKFEVV DIDNYRIDQL 420
LVTRIDSKAT ALSPKLPDAK DKEESVA 447 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. 
Interpro
 IPR016169; CO_DH_flavot_FAD-bd_sub2.
 IPR000644; Cysta_beta_synth_core.
 IPR002550; DUF21.
 IPR005170; Transptr-assoc_dom. 
Pfam
 PF00571; CBS
 PF03471; CorC_HlyC
 PF01595; DUF21 
SMART
 SM00116; CBS
 SM01091; CorC_HlyC 
PROSITE
 PS51371; CBS 
PRINTS