CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005036
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chromosomal protein D1 
Protein Synonyms/Alias
  
Gene Name
 D1 
Gene Synonyms/Alias
 CG9745 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
288KPRSRPAKNIDDDADacetylation[1]
308DQGQHNSKKESNDEDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 This satellite DNA-associated protein is a double- stranded DNA binding protein specific for tracts of pure at DNA. It may play a role in organizing the higher-order structure of euchromatin as well as heterochromatin. 
Sequence Annotation
 DNA_BIND 7 14 A.T hook 1.
 DNA_BIND 34 41 A.T hook 2.
 DNA_BIND 60 67 A.T hook 3.
 DNA_BIND 94 101 A.T hook 4.
 DNA_BIND 122 129 A.T hook 5.
 DNA_BIND 155 162 A.T hook 6.
 DNA_BIND 174 181 A.T hook 7.
 DNA_BIND 196 203 A.T hook 8.
 DNA_BIND 219 226 A.T hook 9.
 DNA_BIND 262 269 A.T hook 10.
 DNA_BIND 281 288 A.T hook 11.
 MOD_RES 1 1 N-acetylmethionine (Probable).
 MOD_RES 30 30 Phosphoserine.
 MOD_RES 80 80 Phosphoserine.
 MOD_RES 88 88 Phosphoserine.
 MOD_RES 89 89 Phosphoserine.
 MOD_RES 107 107 Phosphoserine.
 MOD_RES 109 109 Phosphoserine.
 MOD_RES 112 112 Phosphoserine.
 MOD_RES 115 115 Phosphothreonine.
 MOD_RES 118 118 Phosphoserine.
 MOD_RES 133 133 Phosphoserine; by CK2 (Potential).
 MOD_RES 135 135 Phosphoserine; by CK2 (Potential).
 MOD_RES 149 149 Phosphoserine.
 MOD_RES 150 150 Phosphoserine.
 MOD_RES 161 161 Phosphoserine.
 MOD_RES 164 164 Phosphoserine.
 MOD_RES 170 170 Phosphoserine.
 MOD_RES 186 186 Phosphoserine; by CK2 (Potential).
 MOD_RES 208 208 Phosphoserine.
 MOD_RES 246 246 Phosphoserine.
 MOD_RES 252 252 Phosphoserine.
 MOD_RES 253 253 Phosphoserine.
 MOD_RES 299 299 Phosphoserine.
 MOD_RES 307 307 Phosphoserine.
 MOD_RES 311 311 Phosphoserine; by CK2 (Potential).
 MOD_RES 321 321 Phosphothreonine.
 MOD_RES 332 332 Phosphoserine; by CK2 (Potential).  
Keyword
 Acetylation; Chromosome; Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 355 AA 
Protein Sequence
MEEVAVKKRG RPSKASVGGK SSTAAVAAIS PGIKKRGRPA KNKGSSGGGG QRGRPPKASK 60
IQNDEDPEDE GEEDGDGDGS GAELANNSSP SPTKGRGRPK SSGGAGSGSG DSVKTPGSAK 120
KRKAGRPKKH QPSDSENEDD QDEDDDGNSS IEERRPVGRP SAGSVNLNIS RTGRGLGRPK 180
KRAVESNGDG EPQVPKKRGR PPQNKSGSGG STGYVPTGRP RGRPKANAAP VEKHEDNDDD 240
QDDENSGEEE HSSPEKTVVA PKKRGRPSLA AGKVSKEETT KPRSRPAKNI DDDADDADSA 300
DQGQHNSKKE SNDEDRAVDG TPTKGDGLKW NSDGENDAND GYVSDNYNDS ESVAA 355 
Gene Ontology
 GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0003696; F:satellite DNA binding; IDA:FlyBase. 
Interpro
 IPR020478; AT_hook-like.
 IPR017956; AT_hook_DNA-bd_motif. 
Pfam
 PF02178; AT_hook 
SMART
 SM00384; AT_hook 
PROSITE
  
PRINTS
 PR00929; ATHOOK.