CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014911
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SET and MYND domain-containing protein 5 
Protein Synonyms/Alias
 Protein NN8-4AG; Retinoic acid-induced protein 15 
Gene Name
 SMYD5 
Gene Synonyms/Alias
 RAI15 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
105PELCTVRKDLHQNCPubiquitination[1]
150DPLHPLNKLQEAWRSubiquitination[1]
196LFSQFCNKTANEEEEubiquitination[1]
207EEEEIVHKLLGDKFKubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 DOMAIN 21 352 SET.
 ZN_FING 98 136 MYND-type.  
Keyword
 Complete proteome; Metal-binding; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 418 AA 
Protein Sequence
MAASMCDVFS FCVGVAGRAR VSVEVRFVSS AKGKGLFATQ LIRKGETIFV ERPLVAAQFL 60
WNALYRYRAC DHCLRALEKA EENAQRLTGK PGQVLPHPEL CTVRKDLHQN CPHCQVMYCS 120
AECRLAATEQ YHQVLCPGPS QDDPLHPLNK LQEAWRSIHY PPETASIMLM ARMVATVKQA 180
KDKDRWIRLF SQFCNKTANE EEEIVHKLLG DKFKGQLELL RRLFTEALYE EAVSQWFTPD 240
GFRSLFALVG TNGQGIGTSS LSQWVHACDT LELKPQDREQ LDAFIDQLYK DIEAATGEFL 300
NCEGSGLFVL QSCCNHSCVP NAETSFPENN FLLHVTALED IKPGEEICIS YLDCCQRERS 360
RHSRHKILRE NYLFVCSCPK CLAEADEPNV TSEEEEEEEE EEEGEPEDAE LGDEMTDV 418 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR001214; SET_dom. 
Pfam
 PF00856; SET 
SMART
 SM00317; SET 
PROSITE
 PS50280; SET
 PS01360; ZF_MYND_1
 PS50865; ZF_MYND_2 
PRINTS