| Tag | Content |
|---|
| CPLM ID | CPLM-007342 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 6-phosphofructo-2-kinase 1 |
Protein Synonyms/Alias | 6PF-2-K 1; Phosphofructokinase 2 I |
Gene Name | PFK26 |
Gene Synonyms/Alias | YIL107C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MFKPVDFSET | acetylation | [1] |
|
Reference | [1] Lysine 3 acetylation regulates the phosphorylation of yeast 6-phosphofructo-2-kinase under hypo-osmotic stress. Dihazi H, Kessler R, Müller GA, Eschrich K. Biol Chem. 2005 Sep;386(9):895-900. [ PMID: 16164414] |
Functional Description | Synthesis of fructose 2,6-bisphosphate. |
Sequence Annotation | NP_BIND 190 197 ATP (Potential).
ACT_SITE 277 277 Potential.
ACT_SITE 309 309 Potential.
ACT_SITE 404 404 Phosphoserine intermediate (By
ACT_SITE 497 497 Potential.
ACT_SITE 565 565 Proton donor (By similarity).
BINDING 343 343 Fructose-6-phosphate (By similarity).
MOD_RES 92 92 Phosphoserine.
MOD_RES 157 157 Phosphothreonine.
MOD_RES 644 644 Phosphoserine.
MOD_RES 652 652 Phosphoserine.
MOD_RES 659 659 Phosphoserine.
MOD_RES 667 667 Phosphoserine. |
Keyword | ATP-binding; Complete proteome; Direct protein sequencing; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 827 AA |
Protein Sequence | MFKPVDFSET SPVPPDIDLA PTQSPHHVAP SQDSSYDLLS RSSDDKIDAE KGPHDELSKH 60
LPLFQKRPLS DTPISSNWNS PGITEENTPS DSPENSATNL KSLHRLHIND ETQLKNAKIP 120
TNDTTDYMPP SDGANEVTRI DLKDIKSPTR HHKRRPTTID VPGLTKSKTS PDGLISKEDS 180
GSKLVIVMVG LPATGKSFIT NKLSRFLNYS LYYCKVFNVG NTRRKFAKEH GLKDQDSKFF 240
EPKNADSTRL RDKWAMDTLD ELLDYLLEGS GSVGIFDATN TSRERRKNVL ARIRKRSPHL 300
KVLFLESVCS DHALVQKNIR LKLFGPDYKG KDPESSLKDF KSRLANYLKA YEPIEDDENL 360
QYIKMIDVGK KVIAYNIQGF LASQTVYYLL NFNLADRQIW ITRSGESEDN VSGRIGGNSH 420
LTPRGLRFAK SLPKFIARQR EIFYQNLMQQ KKNNENTDGN IYNDFFVWTS MRARTIGTAQ 480
YFNEDDYPIK QMKMLDELSA GDYDGMTYPE IKNNFPEEFE KRQKDKLRYR YPGIGGESYM 540
DVINRLRPVI TELERIEDNV LIITHRVVAR ALLGYFMNLS MGIIANLDVP LHCVYCLEPK 600
PYGITWSLWE YDEASDSFSK VPQTDLNTTR VKEVGLVYNE RRYSVIPTAP PSARSSFASD 660
FLSRKRSNPT SASSSQSELS EQPKNSVSAQ TGSNNTTLIG SNFNIKNENG DSRIPLSAPL 720
MATNTSNNIL DGGGTSISIH RPRVVPNQNN VNPLLANNNK AASNVPNVKK SAATPRQIFE 780
IDKVDEKLSM LKNKSFLLHG KDYPNNADNN DNEDIRAKTM NRSQSHV 827 |
Gene Ontology | GO:0005737; C:cytoplasm; IC:SGD. GO:0003873; F:6-phosphofructo-2-kinase activity; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:InterPro. GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IMP:SGD. GO:0006000; P:fructose metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |