CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016009
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ectopic P granules protein 5 homolog 
Protein Synonyms/Alias
  
Gene Name
 Epg5 
Gene Synonyms/Alias
 Kiaa1632 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
252PEVTPFTKEQLKLLEubiquitination[1]
1615QQIHVLQKEVRQLQAacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
 Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo (By similarity). 
Sequence Annotation
  
Keyword
 Autophagy; Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2572 AA 
Protein Sequence
MAEAVKPRRA KAKASRTKGK EKKKHEALQT CDAGPLPETC REQESPCPAS ELKGDDLKSS 60
ADPQLHSDVC GWNESEMFDI PLTSLTIGDE GPPVQDTEDL KERGEVTAGD GDDEMELKVD 120
PGDNVIAKGE PCKNFPEVED HTLIQCGPPE STLQPDFPCT QQAVEGSHAR EHPTRKQDEA 180
ALGCSKVFQN VSLHSSYEAK EVSQPPRVKK LYPELPAEIA EVPALVAVKP LLRSERLYPE 240
LPSQPEVTPF TKEQLKLLEP GSWLENVASY VEEFDNIAHQ DRHEFYELLL NYSRCRKQLL 300
LAEAELLTLM SDCHSAKSRL WHFKDEQMAV QGICADQVKV YGHHHYQRVE MNENVLGELK 360
KLFDAKSEHL HQTLTLHSYT SVLSRLQVES YIFTLLNSSA ALRSLAVYQA DQVPKLTESI 420
PSDVCQLKEC ISVLFMFTRR VSEDAQFHED ILLWLQKLVS VLQRVGCPGD HFFLLNHVLR 480
CPAGIRKWAV PFIQIKVLNN PSGVFHFMQS LALLMSPVKN RAEFMCHMKP SEWKPSSSGP 540
ASGNWTLVDE AGEEDEDPET SWILLNEDDL VTLLSQFPFQ ELFQHLLGFK AKGDYLPETT 600
RPQEMMKIFA FANSLVELLA VGLDTFNRAR YRQFVKRIGY LIRMTLGYVS DHWAQYVSHS 660
TGAGLTPQPY SMEKLQVEFD ELFLRAVLHV LKAKRLGIWL FMSEMPFGTL SVQMLWKLLY 720
LMHQVESGDL QQLCASLQPA ECKRRLQDPE HFASFEKCLS SINSSEEICL LTAFAQMARA 780
RRTNVDEDFI KIIVLEIYEV SYVTLSTRET FSKVGRELLG AIAAVHPEII SVLLDRVQET 840
IDQVGMVSLY LFKELPLYLW RPSAPEIAVI RDWLLNNNLT AVKNKLACVI LEGLNWGFTE 900
QGTLHLDQAL HTEVALLVLE AYQKYLAQKP YTGLISESMK QVSYLASIVR YGETPETSFN 960
QWAWNLILRL KLHKNDFGRQ NFPVIPFCST VPDMTESSMF HPLLKAVKSG LPIGCYLALA 1020
VTAVGHSLEK FCAEGIPLLG VLVQSRHLRA VVHALDKILP VFYPYQCYLL KNEQFLSNLL 1080
LFLQLDSGVP QGVTQQVTHR VAQHLTGAVH GDNVKLLSSM IQAHICVSTQ PDGVGPVAVL 1140
EFWVQALISQ HLWYREQPIL FLMDHLCKTA FHLMQEDCVQ KLLYQQHKNA LGYHCDRSLL 1200
SSLVNWIVAG NITPSFVEGL STSTQVWFAW TVLNMESIFE EDSQLRRVVE RELVINAFSP 1260
DQALKKAQVQ LKLPIVPSLQ RLLIYRWAHQ ALVTPSDHPL LPLIWQKFFL LYLHRPGPQY 1320
GLPVDGCIGR RFFQSPSHVN LLKDMKRRLT EVADFHYAAS KALRVPAEGS EGTPEGQAGT 1380
PGFLTSPELH RELVRLFNVY VLWLEDENFQ KGDTYIPSLP KHYDVHRLAK VMQNQQDLWM 1440
EYVNMERIQH EFQETVALWT QAKLESHAAP CSSSAQLDFT DPLLAKARVL SNLEKHEAPH 1500
PPLLLHPVRP PVPLIPSAAL LTQKDSTQLM CTDLNLLQQQ ARSATLRESQ QVALDGELLE 1560
TMPKQYVNRE DQATLHLECR GSSGKKCQGA AVVTVQFEGM NKNEAVSQQI HVLQKEVRQL 1620
QAEAAQPPAL NVVEAAVHAE NLITALVNTY KLQPTPGVQK LGISLFFTVV DHVSDETQRH 1680
PPTRQFFTSC IEILGQVFVS GTKSECRKLL QTILKNRRLC SLLAPFFTPN AAPAEFIQLY 1740
ERVVTCLRED NSDVIFMLLT KFDIQQWLNS TKPPLSDRTR LLESIHLALT AWGLEPEEDI 1800
LMPFNLFCKH WTHLLLYQFP DQYSDVLRLL VQSSAEQLLS PECWKATLRA LGCYAPSSQQ 1860
GAASVESSGL HSASRVLLSD KQVMETVQWL SDFFYKLRLS KLDFKSFGLF SKWSPYMADV 1920
KTFLGYLVKR LTDLEIASLS QDPTASSKEV LRSLHAQIIQ LFKPWILVLE DAESSHQRHY 1980
PWLESDTAVA SSIVQLFSDC VGSLHTSFKD RLLPGDEGAL RLHLLHYCET CTAPKMPEFI 2040
LYAFHSAYQR LEWKDLHPDQ RLMEAFFKVE RGSPKSCFLF LGSVLCRVNW VSVLSDAWNP 2100
SPLPETQSMA VCLLFMMVLL AKEAQLVDEP DSPLLSLLGQ TSSLSWHLVD LVSYQSVLGY 2160
FSSHYPPSVV LANDCSSELI VKLLKVSAGL SAHADGRKHV DIVPKCQAFT HQMVQFLSAL 2220
EQTGKITFPA LEREISKLLD DIIIFNPPDM DSQTRHMALS SFFVEVLMMM NNAAVPTAEF 2280
LAVSIRTWIG QRVHGLIVLP LLTAACQSLA SVRHMAEITE ACIMAYFKES SLDQNLGWGP 2340
VLVSLQVPQL TARDFLEECL ALGSCLTLYV YLLQCLNSEQ TVKNDMKMLL VVSGWLEQVY 2400
PSSAQEEAKL FLWWHQILQL SLIQLEQNDS VLTESVIRIL LMLQSRQSLM AEERLSSGIL 2460
GAIGLGRRSP LSNRFRVAAR SMAAFLLVQV PAEDQIRLKP SSELHLAPKA QQVLTALESM 2520
TLSKQYVEYQ DQILHALQFI RHPGHCLQNG KSFLALLVNR LYPEVHYLDN IR 2572 
Gene Ontology
 GO:0006914; P:autophagy; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS