CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011620
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable oxidoreductase ENV9 
Protein Synonyms/Alias
 Late endosome and vacuole interface protein 9 
Gene Name
 ENV9 
Gene Synonyms/Alias
 YOR246C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
52ICGRNSHKISKAIQEubiquitination[1]
287DPNLSVEKDNGKYFTubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Probable dehydrogenase required for replication of Brome mosaic virus. Involved in vacuolar processing and morphology. 
Sequence Annotation
 NP_BIND 47 53 NAD or NADP (By similarity).
 ACT_SITE 202 202 Proton acceptor (By similarity).
 BINDING 173 173 Substrate (By similarity).
 CARBOHYD 282 282 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Lipid droplet; Membrane; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 330 AA 
Protein Sequence
MLDPRILPYY DPAVERKIAV VTGGNTGIGW YTVLHLYLHG FVVYICGRNS HKISKAIQEI 60
LAEAKKRCHE DDDGSSPGAG PGPSIQRLGS LHYIHLDLTD LKCVERAALK ILKLEDHIDV 120
LVNNAGIMAV PLEMTKDGFE VQLQTNYISH FIFTMRLLPL LRHCRGRIIS LSSIGHHLEF 180
MYWKLSKTWD YKPNMLFTWF RYAMSKTALI QCTKMLAIKY PDVLCLSVHP GLVMNTNLFS 240
YWTRLPIVGI FFWLLFQVVG FFFGVSNEQG SLASLKCALD PNLSVEKDNG KYFTTGGKES 300
KSSYVSNNVD EAASTWIWTV HQLRDRGFDI 330 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005811; C:lipid particle; IDA:SGD.
 GO:0016491; F:oxidoreductase activity; ISS:SGD.
 GO:0006624; P:vacuolar protein processing; IMP:SGD.
 GO:0007033; P:vacuole organization; IMP:SGD. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.