CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040492
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Sp140 
Protein Synonyms/Alias
  
Gene Name
 Sp140 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
380KIPAGKSKKRRRKKKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 722 AA 
Protein Sequence
MAGGDNGLSS RMIPENQNGE QSDDYQLMFK LFKENKVEIA SAITKLFPFL MSLRDRDFIS 60
EQKYQECQET CKNLVPVDRV VYDILSDIQK KFSRDLLKVI FSNVHLKAYP DLQEILKHFL 120
SVSENHRTVQ RINGRDVEER PRLPAVVREG DYSPERVEMK KIKAEKTPGP LPMCHGMEGR 180
KQSTQSLSGI LICKLMIPKH EPSHLPVSFL SCRPSSYSPG NTQMSAGQAE EVPSLPQCNG 240
GDERDFTCQS AEGRSSPEQM CDGQEPQDNL PSSLRCEAAS CSPGNTQTNA EQAEEAPSLP 300
QCNGREGSSS CEQMCDGPDP QDELSSSLRR DTGAQQPTSE ERCTCVMCSP TYVPEDLEAR 360
MGSSQGAMDT GRKIPAGKSK KRRRKKKGYN WSKPKRRKPM IVRRKYGRRA VTQAVFRRKK 420
MKNPGLSAKI RGPRRHGKEM ANFNAELLPV TCGNLKGVLH KDKFKQGISV MSIQCQDGNW 480
VTPPEFEIMG GHGRSKNWKL SLRCYNWPLK LLIQRNFLPI PPRIYGKRKK KRTQSLHHFP 540
ADPDNSDECE VCRDGGTLFC CDTCSRAFHE ECHIPAVEAE VTPWSCIFCR MQSLGSQQSL 600
PESEILQREM VPQEQLKCEY VLLRVYCCSE SSFFSKMPYY YYFREMAVGV QEPMWLDIIK 660
RKLSDQAYSQ VEDFVQDMRL IFRNHRITFK DPKFGEMGLI LESKFEKSFK EAFAIQGRSE 720
KS 722 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001487; Bromodomain.
 IPR000770; SAND_dom.
 IPR010919; SAND_dom-like.
 IPR004865; Sp100.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00439; Bromodomain
 PF01342; SAND
 PF03172; Sp100 
SMART
 SM00297; BROMO
 SM00249; PHD
 SM00258; SAND 
PROSITE
 PS50014; BROMODOMAIN_2
 PS51414; HSR
 PS50864; SAND
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS