| Tag | Content |
|---|
| CPLM ID | CPLM-018210 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable ATP-dependent RNA helicase DHX36 |
Protein Synonyms/Alias | DEAH box protein 36; MLE-like protein 1; RNA helicase associated with AU-rich element ARE |
Gene Name | Dhx36 |
Gene Synonyms/Alias | Ddx36; Kiaa1488; Mlel1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 763 | FEGWEEAKRRGFRYE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis (By similarity). |
Sequence Annotation | DOMAIN 210 380 Helicase ATP-binding.
DOMAIN 470 640 Helicase C-terminal.
NP_BIND 223 230 ATP (By similarity).
MOTIF 327 330 DEAH box.
MOD_RES 940 940 N6-acetyllysine (By similarity). |
Keyword | Acetylation; ATP-binding; Coiled coil; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1001 AA |
Protein Sequence | MSYDYHQSWS RDGGPRGSGQ GSSGGGGGGS RGSGGGGGGR GGRGRHPAHL KGREIGLWYA 60
KKQTQKNKEA ERQERAVVHM DERREEQIVQ LLNSVQAKTD KDSEAQISWF APEDHGYGTE 120
VSSEKKINSE KKLDNQEKKL LNQEKKTFRI TDKSYIDRDS EYLLQENEPN LSLDQHLLED 180
LQRKKTDPRY IEMQRFRKKL PSYGMQKELV NLINNHQVTV ISGETGCGKT TQVTQFILDN 240
YIERGKGSAC RIVCTQPRRI SAISVAERVA TERAESCGNG NSTGYQIRLQ SRLPRKQGSI 300
LYCTTGIILQ WLQSDSRLSS VSHIVLDEIH ERNLQSDVLM TVIKDLLHFR SDLKVILMSA 360
TLNAEKFSEY FGNCPMIHIP GFTFPVVEYL LEDIIEKIRY VPDQKEHRSQ FKRGFMQGHV 420
NRQEKEEKEA IYKERWPAYI KELRTRYSAS TVDVLQMMDD DKVDLNLIAA LIRYIVLEEE 480
DGAILVFLPG WDNISTLHDL LMSQVMFKSD KFLIIPLHSL MPTVNQTQVF KKTPPGVRKI 540
VIATNIAETS ITIDDVVYVI DGGKIKETHF DTQNNISTMS AEWVSKANAK QRKGRAGRVQ 600
PGHCYHLYNG LRASLLDDYQ LPEILRTPLE ELCLQIKILR LGGIAYFLSR LMDPPSNEAV 660
VLSIKHLMEL SALDKQEELT PLGVHLARLP VEPHIGKMIL FGALFCCLDP VLTIAASLSF 720
KDPFVIPLGK EKIADARRKE LAKETRSDHL TVVNAFEGWE EAKRRGFRYE KDYCWEYFLS 780
SNTLQMLHNM KGQFAEHLLG AGFVSSRSPK DPKANINSDN EKIIKAVICA GLYPKVAKIR 840
LNLGKKRKMV KVHTKSDGLV SIHPKSVNVE QTDFHYNWLI YHLKMRTSSI YLYDCTEVSP 900
YCLLFFGGDI SIQKDKDQEI IAVDEWIVFQ SPERIAHLVK GLRKELDSLL QEKIESPHPV 960
DWDDTKSRDC AVLSAILDLI KTQEKATPRN LPPRSQDGYY S 1001 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |