CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013000
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable RNA-binding protein EIF1AD 
Protein Synonyms/Alias
 Eukaryotic translation initiation factor 1A domain-containing protein 
Gene Name
 Eif1ad 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
29SDHQQIVKVLRTPGNacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
 Plays a role into cellular response to oxidative stress. Decreases cell proliferation (By similarity). 
Sequence Annotation
 DOMAIN 5 89 S1-like.
 MOTIF 6 12 Nuclear localization signal (Potential).
 MOTIF 56 65 Nuclear localization signal (Potential).
 MOD_RES 33 33 Phosphothreonine (By similarity).
 MOD_RES 155 155 Phosphoserine (By similarity).
 MOD_RES 159 159 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 170 AA 
Protein Sequence
MSQASKRKHV VQEVLGEHMV PSDHQQIVKV LRTPGNNLHE VETAQGQRFL VSMPSKYRKN 60
IWIKRGDFLI VDPIEEGEKV KAEISFVLCK NHVRSLQKEG HWPEAFSEVA EKQNNMNRES 120
QPELPAEPQL SGEGSSSEDD SDLFVNTNHR QYHESEEESE EDEEEEEEAA 170 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003743; F:translation initiation factor activity; IEA:InterPro. 
Interpro
 IPR012340; NA-bd_OB-fold.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR001253; TIF_eIF-1A. 
Pfam
 PF01176; eIF-1a 
SMART
 SM00652; eIF1a 
PROSITE
 PS50832; S1_IF1_TYPE 
PRINTS