| Tag | Content |
|---|
| CPLM ID | CPLM-006365 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Homeobox protein YOX1 |
Protein Synonyms/Alias | |
Gene Name | YOX1 |
Gene Synonyms/Alias | YML027W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 336 | SPNSRVNKLINSIDH | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Transcriptional repressor required to restrict transcription of ECB-dependent genes to the G1/M phase by repressing their transcription during the interval from late G1 to M phases. Genes that contain a ECB (early cell box) element in their transcription regulatory region are transcribed only during G1/M phases. In vitro, is capable of binding to the DNA of the leucine tRNA gene. |
Sequence Annotation | DNA_BIND 176 235 Homeobox. |
Keyword | Cell cycle; Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 385 AA |
Protein Sequence | MSQETKMLPS LSSLLSGTEI SSSPVSPSFT NPRTSFHLDD RGTIKLPPLN TSINRPRSVE 60
SALRHTVTSL HENSSAYGDD MLKHTQSDSA LSSQLNSSQE TVDESHENLL LTPLNSKKRD 120
YSVSSKKNDI LTPLSAAKSI IIPSASKEKR RAFAFITHSQ ETFPKKEPKI DNAPLARRKR 180
RRTSSQELSI LQAEFEKCPA PSKEKRIELA ESCHMTEKAV QIWFQNKRQA VKRQRIATSK 240
STTIIQTVSP PSPPLDVHAT PLASRVKADI LRDGSSCSRS SSSSPLENTP PRPHHSLNRR 300
SSTPSIKRSQ ALTFHLNPQK KTLTPVKTSP NSRVNKLINS IDHSPSKAKR PVSNPSGSPK 360
RKRKFGFKIV DQQPLKDLDP NAFRG 385 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0000790; C:nuclear chromatin; IDA:SGD. GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD. GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IMP:SGD. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD. |
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