CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019044
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clusterin-associated protein 1 
Protein Synonyms/Alias
 Qilin 
Gene Name
 CLUAP1 
Gene Synonyms/Alias
 KIAA0643 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
95QADGYAVKELLKITSubiquitination[1]
133FKFDLGSKIADLKAAubiquitination[1]
138GSKIADLKAARQLASubiquitination[1]
190KVMRIAIKEILTQVQubiquitination[1]
200LTQVQKTKDLLNNVAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity). 
Sequence Annotation
 MOD_RES 409 409 Phosphoserine.  
Keyword
 Alternative splicing; Cell projection; Cilium; Cilium biogenesis/degradation; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 413 AA 
Protein Sequence
MSFRDLRNFT EMMRALGYPR HISMENFRTP NFGLVSEVLL WLVKRYEPQT DIPPDVDTEQ 60
DRVFFIKAIA QFMATKAHIK LNTKKLYQAD GYAVKELLKI TSVLYNAMKT KGMEGSEIVE 120
EDVNKFKFDL GSKIADLKAA RQLASEITSK GASLYDLLGM EVELREMRTE AIARPLEINE 180
TEKVMRIAIK EILTQVQKTK DLLNNVASDE ANLEAKIEKR KLELERNRKR LETLQSVRPC 240
FMDEYEKTEE ELQKQYDTYL EKFQNLTYLE QQLEDHHRME QERFEEAKNT LCLIQNKLKE 300
EEKRLLKSGS NDDSDIDIQE DDESDSELEE RRLPKPQTAM EMLMQGRPGK RIVGTMQGGD 360
SDDNEDSEES EIDMEDDDDE DDDLEDESIS LSPTKPNRRV RKSEPLDESD NDF 413 
Gene Ontology
 GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. 
Interpro
 IPR019366; Clusterin-associated_protein-1. 
Pfam
 PF10234; Cluap1 
SMART
  
PROSITE
  
PRINTS